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Hypercapnic Acute Respiratory Failure in the ICU : the YETI Study

NCT04304339 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 862

Last updated 2025-09-18

No results posted yet for this study

Summary

Hypercapnia is a frequent clinical situation defined as an elevation of the partial pressure of carbon dioxide (PaCO2) above 45 mmHg. Several physiopathological parameters such as respiratory minute volume, dead space volume or CO2 production influence the PaCO2. Therefore, hypercapnia can affect the time of various diseases.

Available epidemiological data regarding hypercapnia are from studies investigating the efficacy of non-invasive ventilation (NIV), with different population cohorts. However, their interpretation must be cautious given the heterogeneity in patient case-mix and results.

Then, whether hypercapnia is a common reason for intensive care unit (ICU) admission, epidemiological data is scarce and heterogeneous. The aim of this study is to investigate the epidemiological, clinical determinants and outcomes of patients admitted to ICU with hypercapnic respiratory failure.

Conditions

  • Intensive Care Unit Syndrome
  • Hypercapnia
  • Acute Respiratory Failure

Interventions

OTHER

Hypercapnic respiratory failure

Patients with hypercapnic respiratory failure will be followed without any additional intervention

Sponsors & Collaborators

  • French Society for Intensive Care

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-12-14
Primary Completion
2022-07-13
Completion
2022-07-13

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04304339 on ClinicalTrials.gov