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Acute Exercise and the Cerebral Metabolic Response in Aging and Alzheimer's Disease

NCT04299308 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2025-07-23

Study results available
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Summary

The overall goal is to characterize the acute exercise response as it relates to brain glucose metabolism in aging and Alzheimer's Disease (AD). The study team will also examine lactate metabolism, relationships with cognition, and the effect of exercise intensity.

Conditions

  • Healthy Aging
  • Alzheimer Disease

Interventions

BEHAVIORAL

Aerobic Exercise

Participants will exercise for 15 minutes based on heart rate range. The study team will employ a stationary bike to maintain control over workload

Sponsors & Collaborators

  • National Institute on Aging (NIA)

    collaborator NIH

  • University of Kansas Medical Center

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-08-28
Primary Completion
2023-10-31
Completion
2023-10-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04299308 on ClinicalTrials.gov