Study to Assess the Safety and Tolerability of Repeated Doses of an Investigational New Drug in Patients With Cancer and Cachexia.
NCT04299048 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 11
Last updated 2023-12-14
Summary
Study to assess the safety and tolerability of repeated doses of an investigational new drug in patients with cancer and cachexia.
Conditions
- Cachexia
- Non-Small-Cell Lung Cancer
- Pancreatic Cancer
- Colorectal Cancer
Interventions
- DRUG
-
PF-06946860
subcutaneous injection
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Pfizer CT.gov Call Center · Pfizer
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SEQUENTIAL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-11-17
- Primary Completion
- 2022-03-30
- Completion
- 2022-03-30
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
A Clinical Study With MT-102 in Subjects With Cancer Cachexia
NCT01238107 ·Status: COMPLETED ·Phase: PHASE2
-
Placebo Controlled, Randomized Safety and Efficacy Study of RC-1291 in Cancer Anorexia/Cachexia
NCT00378131 ·Status: COMPLETED ·Phase: PHASE2
-
Phenylbutyrate in Treating Patients With Refractory Solid Tumors or Lymphoma
NCT00002909 ·Status: COMPLETED ·Phase: PHASE1
-
Safety, Tolerance and Efficacy of an Oral Nutritional Supplement in Lung Cancer Patients
NCT00851448 ·Status: TERMINATED ·Phase: NA
-
AFP464 in Treating Patients With Advanced Solid Tumors
NCT00369200 ·Status: TERMINATED ·Phase: PHASE1
-
Placebo Controlled, Randomized Safety and Efficacy Study of RC-1291 in Cancer Anorexia/Cachexia.
NCT00267358 ·Status: COMPLETED ·Phase: PHASE2
-
A First in Human Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics Effects of OC514
NCT05264038 ·Status: COMPLETED ·Phase: PHASE1
-
Pilot Study of APD209 in Cancer Cachexia
NCT00895726 ·Status: COMPLETED ·Phase: PHASE2
-
Anamorelin Hydrochloride, Physical Activity, and Nutritional Counseling in Decreasing Cancer-Related Fatigue in Patients With Incurable Metastatic or Recurrent Solid Tumors
NCT03035409 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Individual Dose-escalated Bi-daily Subcutaneously (sc) Ghrelin in Cancer Cachexia: a Phase I/II Study
NCT00933361 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Study to Assess the Safety, Tolerability and Pharmacokinetics of TCMCB07 in Single and Multiple Ascending Doses in Health Subjects
NCT05529849 ·Status: COMPLETED ·Phase: PHASE1
-
Prevention of Sagopilone-induced Neurotoxicity With Acetyl-L-Carnitine (ALC)
NCT00751205 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Investigate the Effect of Food on Oral LBH589 Absorption in Patients With Advanced Solid Tumors
NCT00570284 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Efficacy of Armodafinil for Fatigue Associated With Taxanes Alone or in Combination With Other Agents
NCT00825227 ·Status: TERMINATED ·Phase: PHASE2
-
A Pilot Study of Eicosapentaenoic Acid (EPA) in Patients With Cancer Cachexia
NCT00815685 ·Status: COMPLETED ·Phase: NA
-
Frequency of Cachexia in Ambulatory Cancer Patients and Psychological Burden in Patients and Their Primary Caregivers
NCT04090619 ·Status: ACTIVE_NOT_RECRUITING
-
Multimodal Intervention for Cachexia in Advanced Cancer Patients Undergoing Chemotherapy
NCT02330926 ·Status: COMPLETED ·Phase: PHASE3
-
Fenretinide in Treating Patients With Metastatic or Unresectable Malignant Solid Tumors
NCT00387504 ·Status: COMPLETED ·Phase: PHASE1
-
Enteral Nutrition With L-Carnitine for Cachexia in Non-Small Cell Lung Cancer
NCT07035444 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Levocarnitine in Treating Fatigue in Cancer Patients
NCT00091169 ·Status: COMPLETED ·Phase: PHASE3
-
Nabilone Effect on the Attenuation of Anorexia, Nutritional Status and Quality of Life in Lung Cancer Patients
NCT02802540 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Pilot Study to Evaluate Safety & Biological Effects of Orally Administered Reparixin in Early Breast Cancer
NCT01861054 ·Status: TERMINATED ·Phase: PHASE2
-
Testing the Safety and Efficacy of the Addition of a New Anti-cancer Drug, ZEN003694, to Chemotherapy Treatment (Cisplatin and Etoposide or Carboplatin and Paclitaxel) for Adult and Pediatric Patients (12-17 Years) With NUT Carcinoma
NCT05019716 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Pharmacokinetic Study of Skeletal Muscle Area-based Paclitaxel Infusion in Patients With Cancer
NCT05183126 ·Status: RECRUITING ·Phase: PHASE4
-
A Phase II Study of Minocycline and Armodafinil for Reducing the Symptom Burden Produced by Chemoradiation Treatment for Esophageal Cancer
NCT01746043 ·Status: COMPLETED ·Phase: PHASE2