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Methylene Blue and Microcirculation in Septic Shock

NCT04295993 · Status: UNKNOWN · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 32

Last updated 2020-03-05

No results posted yet for this study

Summary

This trial aims to identify the effects of methylene blue infusion on the the micro-circulation in patients with septic shock. The investigators will evaluate various indices of micro-circulation such as: microvascular flow index, the flow heterogeneity index, the total vessel density, the perfused vessel density, and the proportion of perfused vessels.

Conditions

  • Septic Shock

Interventions

DRUG

Methylene Blue

The patient will receive Methylene Blue bolus with a dose of 2 mg/kg over 10 minutes.

DRUG

Norepinephrine infusion

The patient will receive norepinephrine infusion to maintain mean arterial pressure above 65 mmHg

Sponsors & Collaborators

  • Cairo University

    lead OTHER

Principal Investigators

  • Ahmed Mukhtar, Professor · Professor of anesthesia

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-03-10
Primary Completion
2020-09-10
Completion
2020-09-20

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04295993 on ClinicalTrials.gov