Midodrine During Recovery From Septic Shock
NCT02771158 · Status: WITHDRAWN · Phase: PHASE4 · Type: INTERVENTIONAL
Last updated 2017-11-06
Summary
The purpose of this study is to determine whether midodrine administration decreases duration of intravenous vasopressors and intensive care unit length of stay for patients in septic shock.
Conditions
- Hypotension
- Shock, Septic
- Sepsis
Interventions
- DRUG
-
Midodrine
midodrine is metabolized to an active metabolite, desglymidodrine, which is an alpha adrenergic antagonist that causes vasoconstriction of both venous and arterial vasculature, thereby increasing blood pressure
- DRUG
-
placebo will be administered to double blind the study
Sponsors & Collaborators
-
Northwell Health
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- SUPPORTIVE_CARE
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-08-31
- Primary Completion
- 2017-11-01
- Completion
- 2017-11-01
- FDA Drug
- Yes
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