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Invasive Arterio-Venous Fistula Blood Pressure Monitoring & Fluid Dynamics Study

NCT04293614 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 12

Last updated 2023-03-24

No results posted yet for this study

Summary

The surgical formation of an AVF offers a unique example of vascular remodelling and adaption. Yet, the specific factors which elicit remodelling events which determine successful maturation or failure have not been unambiguously determined.

Computational fluid dynamic (CFD) simulations are increasingly been employed to investigate the interaction between local haemodynamics and remodelling and can potentially be used to assist in clinical risk assessment of maturation or failure.

However, these simulations are inextricably linked to their prescribed boundary conditions and are reliant on in vivo measurements of flow and pressure to ensure their validity. This study will compare in vivo measurements of the pressure distribution across an AVF against a representative numerical model.

Conditions

  • Arterio-venous Fistula

Sponsors & Collaborators

  • University of Limerick

    collaborator OTHER

  • University Hospital of Limerick

    lead OTHER

Principal Investigators

  • Eamon Kavanagh, MD FRCSI · University Hospital of Limerick

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-08-14
Primary Completion
2022-12-14
Completion
2023-01-14

Countries

  • Ireland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04293614 on ClinicalTrials.gov