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Critical Respiratory Diseases in Ex-preterm Infants in PICU

NCT04284891 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 202

Last updated 2022-05-02

No results posted yet for this study

Summary

Premature birth is the leading cause of death in children younger than 5 years old worldwide, especially in low- and middle-income countries. Premature infants who survive are at greater risk of a range of short-term and long-term health consequences. Common long-term health morbidities among children who are born prematurely include cerebral palsy, infections (particularly respiratory infections), bronchopulmonary dysplasia, feeding difficulties, hypoxic-ischemic encephalopathy, visual and hearing problems. Re-hospitalization occurs frequently during first few years of life among ex-premature infants with respiratory illness. This leads to increased financial burden for health care system and families. The impact of prematurity on the health care system, especially on pediatric intensive care units (PICUs) has mainly been evaluated in high income countries. Little is known about long term health outcomes of ex-premature infants and their impact on the cost to health care system in low- and middle-income countries. This pilot, single institution, observational study aims to determine the prevalence, course of the diseases, and outcomes of ex-premature infants with respiratory illnesses who are admitted to a PICU of a tertiary children's hospital in Vietnam. Investigators will determine the epidemiology of respiratory illness, and the resource utilization for these children in the PICU. To achieve these aims, the investigators will prospectively screen and recruit all children aged less than 2 years old admitted to the PICU with respiratory illness/failure and collect pertinent clinical data. The study participants will be follow-up until PICU discharge.

Conditions

Sponsors & Collaborators

  • KK Women's and Children's Hospital

    collaborator OTHER_GOV

  • Duke-NUS Graduate Medical School

    collaborator OTHER

  • National Children's Hospital, Vietnam

    lead OTHER

Principal Investigators

  • Phuc H Phan, MD · Vietnam National Children's Hospital

  • Jan Hau Lee, MD · Duke-NUS Medical, Singapore

Eligibility

Min Age
30 Days
Max Age
2 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-11-01
Primary Completion
2021-05-30
Completion
2021-05-30

Countries

  • Vietnam

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04284891 on ClinicalTrials.gov