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Comparison Between Biopsied and Non-biopsied Intracytoplasmatic Sperm Injection (ICSI) Embryos and Natural Pregnancy Embryos

NCT04280757 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 420

Last updated 2023-10-13

No results posted yet for this study

Summary

As Pre Implantation Genetic Screening (PGS) becomes now a replacement modality and trend gaining popularity among physicians and patients on claiming its ability to settle on the simplest genetically normal embryo, so it had been logical to review if taking cells from the embryo in its early development will or won't affect its growth as compared to the previous standard technique of ICSI and in comparison to a normally conceived embryos the study also will question if the parameters of the prenatal biochemical standard parameters will have any differences if the embryo is already genetically tested embryo and compare these parameters with non PGS embryos and normally conceived embryos.

This study is an ambispective, comparative, cohort, observational, single-center study.

The study participants' relevant medical records will be collected and reviewed for the retrospective subjects and after obtaining informed consent for the prospective subjects. The study materials that will be used will include blood tests and ultrasound. The study will involve three study arms

Conditions

  • Women Conceiving by: 1- ICSI-PGS 2- ICSI-non-PGS 3- Spontaneously Conceiving Women

Interventions

PROCEDURE

Biopsied ICSI embryos (PGS)

Biopsied ICSI embryos (PGS)

Sponsors & Collaborators

  • Fetal Medicine Research Center, Spain

    collaborator OTHER

  • Wael Elbanna Clinic

    lead OTHER

Principal Investigators

  • Wael Elbanna, Specialist · Wael Elbanna Clinic

  • Eduard Gratacos, Specialist · fetal medicine

  • Manal El-Hinnawi, Specialist · Wael Elbanna Clinic

Eligibility

Min Age
20 Years
Max Age
40 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-07-01
Primary Completion
2023-11-30
Completion
2024-08-31

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04280757 on ClinicalTrials.gov