MedTrace Logo

Detection of Metabolite Biomarkers for the Early Diagnosis and Prognosis of Cow's Milk Allergy in Children

NCT04249973 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 81

Last updated 2024-04-12

No results posted yet for this study

Summary

In this study, fecal and urine samples will be collected from children diagnosed with :

* IgE mediated cow's milk allergy,
* suspected of a cow's milk allergy, but with negative diagnosis
* IgE mediated food allergy other than cow's milk
* healthy brothers and sisters of the first three groups A subset of patients with IgE-mediated cow's milk allergy will be asked to provide a urine and fecal sample yearly for prognostic purposes.

The samples will be analyzed using a technique called metabolomics to identify biomarker candidates with diagnostic and/or prognostic potential. Additionally, microbiome analysis will be performed to map the microbiome of all groups.

Conditions

Interventions

OTHER

Collection of urine and feces

Urine and feces are collected at the families home. A short questionnaire is filled in by the parents

Sponsors & Collaborators

  • University Ghent

    lead OTHER

Principal Investigators

  • Myriam Van Winckel, Prof · University Ghent

Eligibility

Max Age
5 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-01-26
Primary Completion
2025-03-31
Completion
2025-03-31

Countries

  • Belgium

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04249973 on ClinicalTrials.gov