Tuberculosis In Children Visiting Friends and Relatives

Summary

In countries with a low incidence of Tuberculosis (TB), the incidence remains higher among the immigrant population than among the autochthonous population beyond the first years after arrival in the host country. In addition, at a pediatric level, most cases are produced in immigrant children and the children of immigrants. This persistence of a greater incidence in the immigrant population might, in part, be explained by the increase in exposure to Mycobacterium tuberculosis during trips to their country of origin to visit friends and relatives (VFRs). The objectives of the study are to estimate the risk of latent infection by M. tuberculosis (LTBI)/TB in children VFRs and the factors associated with this risk. The investigators will also study the behavior of the diagnostic tests. This project will be carried out in collaboration with 21 primary health care centers and 5 hospitals in Catalonia.

Conditions

• Tuberculosis Infection

Interventions

OTHER

TB infection-screening benefiting group

The children who participate in the study will be recruited during a programmed visit to a traveler health clinic or a primary care center. During the first visit the parents or legal guardian will be interviewed, a questionnaire will be completed with sociodemographic, epidemiologic and clinical data and a tuberculin skin test (TST) will be performed and read at 48-72 hours. At 8-12 weeks after returning from the travel abroad the child will have a new visit. A new interview will be carried out with the parents or legal guardian and a questionnaire will be completed with epidemiological and clinical data. The child will undergo a new TST and QFT-Plus test.

Sponsors & Collaborators

• Public Health Agency of Barcelona

  collaborator OTHER

• Hospital Vall d'Hebron

  collaborator OTHER

• Hospital Sant Joan de Deu

  collaborator OTHER

• Institut Català de la Salut

  collaborator OTHER

• Hospital Universitari Sant Joan de Reus

  collaborator OTHER

• Hospital de Tortosa Verge de la Cinta

  collaborator UNKNOWN

• Hospital Mutua de Terrassa

  lead OTHER

Study Design

Allocation

NA

Purpose

SCREENING

Masking

NONE

Model

SINGLE_GROUP

Eligibility

Min Age

6 Months

Max Age

14 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2018-01-01

Primary Completion

2020-12-31

Completion

2020-12-31

Countries

• Spain

Study Locations