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fNIRS Studies of Music Intervention of Parkinson's Disease

NCT04212897 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 150

Last updated 2021-08-23

No results posted yet for this study

Summary

Functional near-infrared spectroscopy (fNIRS) will be used to monitor neuronal activities and connectivity to elucidate the correlation between physiological changes within the brain and the benefits of music therapy for patients afflicted with Parkinson's disease (PD). This study will report on the changes in neural activities as a result of music intervention in PD.

Conditions

  • Parkinson Disease

Interventions

OTHER

Music Therapy

Participants in the intervention arm will be asked to practice a rhythmic auditory synchronous finger tapping intervention task at home for a total of 25 minutes split between two ten-minute sets with a five-minute break between the sets every day for 8-weeks. During training sessions participants must listen to the instrumental of a pre-selected well-known Chinese melody, "Moonlight over the Lotus Pond" by Phoenix Legend, whose melody duration is 259s. This song was selected for its strong beat and familiarity to the participants. Participants must follow the beats of the melody and tap their right index finger simultaneously to the beats. A visual cue will be displayed to indicate the beats, identical to the one in the assessment. The training session will be conducted once daily after patients have taken their medication. Participants' primary caretaker will be asked to monitor and record completion of sessions.

Sponsors & Collaborators

  • Dalian University of Technology

    collaborator UNKNOWN

  • University of California, Irvine

    collaborator OTHER

  • The First Affiliated Hospital of Dalian Medical University

    lead OTHER

Principal Investigators

  • Zhanhua Liang, MD · The First Affiliated Hospital of Dalian Medical University

  • Bingwei Zhang, MD · The First Affiliated Hospital of Dalian Medical University

  • Fengyu Cong, PhD · Dalian University of Technology

  • William C Tang, PhD · University of California, Irvine

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
40 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-01-18
Primary Completion
2021-12-31
Completion
2022-01-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04212897 on ClinicalTrials.gov