GP96 Heat Shock Protein-Peptide Complex Vaccine in Treating Patients With Liver Cancer
NCT04206254 · Status: UNKNOWN · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 80
Last updated 2019-12-20
Summary
This trial is to further study the safety and effectiveness of autologous gp96 treatment of liver cancer on the basis of preliminary work
Conditions
Interventions
- BIOLOGICAL
-
gp96
heat shock protein gp96-peptide complex made from a person's tumor cells may help the body build an effective immune response to kill tumor cells.
Sponsors & Collaborators
-
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
collaborator OTHER -
Cure&Sure Biotech Co., LTD
lead INDUSTRY
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-12-19
- Primary Completion
- 2022-08-05
- Completion
- 2023-08-05
More Related Trials
-
Study of Tyroserleutide for Injection in Hepatocellular Carcinoma (HCC) Patients
NCT01489566 ·Status: UNKNOWN ·Phase: PHASE3
-
PD-1 mRNA LNP Vaccine for Advanced Primary Hepatocellular Carcinoma.
NCT07053072 ·Status: RECRUITING ·Phase: PHASE1
-
Clinical Study of SN301A Injection in the Treatment of Hepatocellular Carcinoma
NCT06652243 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
Clinical Study of mRNA Vaccine in Patients With Liver Cancer After Operation
NCT05761717 ·Status: UNKNOWN ·Phase: NA
-
Novel GPC3 CAR-T Cell Therapy for Hepatocellular Carcinoma
NCT05344664 ·Status: UNKNOWN ·Phase: PHASE1
-
IMA970A Plus CV8102 in Very Early, Early and Intermediate Stage Hepatocellular Carcinoma Patients
NCT03203005 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Immune Checkpoint Inhibitor Monotherapy or Combined With Molecular Targeted Drugs / Locoregional Therapy in the Treatment of Hepatocellular Carcinoma
NCT05609695 ·Status: UNKNOWN
-
Application of mRNA Immunotherapy Technology in Hepatitis B Virus-related Refractory Hepatocellular Carcinoma
NCT05738447 ·Status: UNKNOWN ·Phase: PHASE1
-
Hepatic Artery Transfusion of NKG2D CAR-NK Cells Followed by Intravenous Infusion of NKG2D CAR-T Cells to Treat Patients With Advanced Solid Tumors With Liver Metastases Who Have Failed Standard Treatments: a Phase I Exploratory Clinical Trial
NCT07021534 ·Status: RECRUITING ·Phase: PHASE1
-
Comparison of Microwave and Radiofrequency Ablation for Liver
NCT02539212 ·Status: COMPLETED ·Phase: NA
-
A Study of Chimeric Antigen Receptor T Cells Combined With Interventional Therapy in Advanced Liver Malignancy
NCT02959151 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
To Evaluate the Safety and Efficacy of Microwave Ablation Therapy in Patients With Primary Liver Cancer
NCT04520906 ·Status: TERMINATED ·Phase: NA
-
Vaccine Therapy in Treating Patients With Stage II, Stage IIIA, Stage IIIB, or Stage IVA Liver Cancer
NCT00093548 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
Combined Locoregional Treatment With Immunotherapy for Unresectable HCC.
NCT04220944 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
ET 140202 -T Cell Combined With TAE or Sorafenib in the Treatment of Liver Cancer
NCT03965546 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
GPC3-CAR-T Cells for the Hepatocellular Carcinoma
NCT04506983 ·Status: SUSPENDED ·Phase: PHASE1
-
Study of Microwave Spherical Ablation and Traditional Microwave Ablation in Single Hepatocellular Carcinoma ≤5cm
NCT05361538 ·Status: UNKNOWN ·Phase: NA
-
Hyperthermia Combined With Immune Checkpoint Inhibitors in the Treatment of Advanced Gastrointestinal Malignancies With Liver Metastases
NCT07118566 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
GPC3-CAR-T Cells for Immunotherapy of Cancer With GPC3 Expression
NCT03198546 ·Status: RECRUITING ·Phase: PHASE1
-
Phase I Clinical Trial of CT0180 Cells in the Treatment of Hepatocellular Carcinoma
NCT04756648 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
GPC3-targeting CART Cell in Treatment of Advanced Hepatocellular Carcinoma
NCT05352542 ·Status: TERMINATED ·Phase: PHASE1
-
A Study to Evaluate C-CAR031 in Glypican-3 (GPC3)+ Advanced/Recurrent Hepatocellular Carcinoma (HCC)
NCT06590246 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Combined Immunotherapy and Targeted Therapy for Hepatocellular Carcinoma
NCT04152356 ·Status: UNKNOWN
-
Clinical Study on the Efficacy and Safety of c-Met/PD-L1 CAR-T Cell Injection in the Treatment of HCC
NCT03672305 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Clinical Feasibility of Microwave Ablation Using Two Channel Microwave Generator and Two Antennas for Small Hepatocellular Carcinoma
NCT06086002 ·Status: COMPLETED ·Phase: NA