Methotrexate Polyglutamate Measurements in Patients With Inflammatory Bowel Disease
NCT04205734 · Status: SUSPENDED · Type: OBSERVATIONAL · Enrollment: 100
Last updated 2023-10-10
Summary
There are currently no serum levels to help guide appropriate methotrexate therapy. Data from this study will assess the correlation between dosing and whole blood methotrexate(MTX) polyglutamate measurements in children and adolescents with IBD.
Conditions
Interventions
- DIAGNOSTIC_TEST
-
MTX Assessment
Measurement of Methotrexate Polyglutamate levels.
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
PAUL A RUFO · Boston Children's Hospital
Eligibility
- Min Age
- 1 Year
- Max Age
- 21 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-01-30
- Primary Completion
- 2024-12-31
- Completion
- 2024-12-31
Countries
- United States
Study Locations
More Related Trials
-
Evaluation of Urinary Isoprostanes in the Assessment of Children With Inflammatory Bowel Disease
NCT00215020 ·Status: COMPLETED
-
Biofeedback in Pediatric Inflammatory Bowel Disease
NCT04269720 ·Status: WITHDRAWN ·Phase: NA
-
Assessment of Metformin as Adjuvant Therapy in Patients With Ulcerative Colitis
NCT04750135 ·Status: UNKNOWN ·Phase: PHASE2
-
Pharmacokinetics of Adalimumab With Methotrexate for Treatment of Patients With Ulcerative Colitis (UC)
NCT01716039 ·Status: TERMINATED ·Phase: PHASE2
-
Safety and Efficacy of MMX Mesalamine/Mesalazine in Pediatric Subjects With Mild to Moderate Ulcerative Colitis
NCT02093663 ·Status: COMPLETED ·Phase: PHASE3
-
Fecal Microbiota Transplant (FMT) in Pediatric Active Ulcerative Colitis and Pediatric Active Crohn's Colitis
NCT02330653 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Impaired Insulin-like Growth Factor-1 (IGF-1) Generation Causes Protein Catabolism and Poor Growth in Children With Crohn Disease
NCT00946361 ·Status: TERMINATED
-
Study of the Pharmacokinetics of Golimumab in Moderate to Severe Ulcerative Colitis
NCT02277470 ·Status: UNKNOWN
-
Non Invasive Characterization of Pediatric Inflammatory Bowel Diseases Using Multispectral Optoacoustic Tomography
NCT04650867 ·Status: COMPLETED
-
A Study to Evaluate Safety and Efficacy of Telotristat Etiprate (LX1606) in Participants With Acute, Mild to Moderate Ulcerative Colitis
NCT01456052 ·Status: COMPLETED ·Phase: PHASE2
-
A Pilot Study Testing the Safety and Feasibility of Restorative Microbiota Therapy (RMT) in Patients With Refractory Immune-checkpoint Inhibitor-related Colitis
NCT05726396 ·Status: WITHDRAWN ·Phase: PHASE2
-
Reduce Risk for Crohn's Disease Patients
NCT02852694 ·Status: COMPLETED ·Phase: PHASE4
-
A Multicenter, Prospective, Long-term, Observational Registry of Pediatric Patients With Inflammatory Bowel Disease
NCT00606346 ·Status: ACTIVE_NOT_RECRUITING
-
High Dose Steroid Therapy to Treat Flares in Patients With Inflammatory Bowel Disease (IBD)
NCT05587673 ·Status: COMPLETED ·Phase: PHASE1
-
An Efficacy and Safety Study of Golimumab in Participants With Ulcerative Colitis
NCT00488774 ·Status: TERMINATED ·Phase: PHASE2/PHASE3
-
Second Line Induction Therapy and Healthy Diet for Patients With Ulcerative Colitis
NCT04505410 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Assess the Safety and Pharmacokinetics of Subcutaneously Administered Golimumab, a Human Anti-TNFα Antibody, in Pediatric Patients With Moderate to Severe Active Ulcerative Colitis
NCT01900574 ·Status: COMPLETED ·Phase: PHASE1
-
Study Evaluating the Persistence, Efficacy and Tolerability of Methotrexate in Inflammatory Bowel Disease Patients
NCT05927064 ·Status: COMPLETED
-
Efficacy and Safety of LC51-0255 in Subjects With Ulcerative Colitis
NCT04096573 ·Status: WITHDRAWN ·Phase: PHASE2
-
Ex-vivo Confocal Imaging and Proteomic Profiling to Determine Treatment Response in Children With IBD
NCT07121920 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Safety and Efficacy Study of PTG-100 in the Treatment of Moderate to Severe Ulcerative Colitis
NCT02895100 ·Status: TERMINATED ·Phase: PHASE2
-
Peer Mentoring to Improve Self-management in Youth With IBD
NCT03827109 ·Status: TERMINATED ·Phase: NA
-
A Study to Assess the Efficacy and Safety of Golimumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis
NCT03596645 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
The Role of PET/MRI in the Diagnosis and Treatment of Children and Adolescents With Inflammatory Bowel Diseases
NCT03640637 ·Status: UNKNOWN
-
Targeted Metabolomics to Decipher Dietary Contributions to Pediatric Inflammatory Bowel Disease (IBD) - Main Study
NCT05014243 ·Status: UNKNOWN