Short Term Effect of Empagliflozin in Hypertension
NCT04203914 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 15
Last updated 2019-12-23
Summary
The investigators assessed the 6-week effect of once daily 25mg SGLT2-i Empagliflozin on left ventricular diastolic function and blood pressure profile in non diabetic hypertensive patients
Conditions
Interventions
- DRUG
-
Empagliflozin Tablets
Add-on 25mg once daily
Sponsors & Collaborators
-
Yaounde Central Hospital
lead OTHER_GOV
Principal Investigators
-
Jean Claude Mbanya, MD, PhD · University of Yaounde 1, Cameroon
-
Eugene Sobngwi, MD, PhD · University of Yaounde 1, Cameroon
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 21 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-01-10
- Primary Completion
- 2017-05-30
- Completion
- 2017-09-30
Countries
- Cameroon
Study Locations
More Related Trials
-
Valsartan Versus Amlodipine Effect on Left Ventricular Multidirectional Deformation and Adipocytokines Level
NCT03990480 ·Status: COMPLETED ·Phase: PHASE4
-
SGLT2 Inhibition for Cardiovascular Endpoint Reduction in Hypertension
NCT06804161 ·Status: RECRUITING ·Phase: PHASE3
-
Optimal Blood Pressure for the prevenTIon of Major vAscuLar Events in Patients With DIABETES Mellitus (OPTIMAL-DIABETES)
NCT04040634 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Efficacy and Safety of Valsartan Plus Hydrochlorothiazide in Patients With Slight Hypertension and Target Organ Damage
NCT00687206 ·Status: COMPLETED ·Phase: PHASE4
-
Educational Intervention for Sodium Restriction in Patients With Hypertension
NCT02848690 ·Status: UNKNOWN ·Phase: NA
-
Early Metabolic Changes With Thiazide or Beta Blocker Therapy for Essential Hypertension
NCT00380289 ·Status: UNKNOWN ·Phase: NA
-
Blood Pressure Reduction in Heart Failure
NCT01255475 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Natriuretic Peptide System as Therapy in Human Preclinical Left Ventricle Dysfunction
NCT00387621 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
The Effect of Spironolactone on Blood Pressure in Type-2 Diabetics With Resistant Hypertension
NCT01062763 ·Status: COMPLETED ·Phase: PHASE3
-
HaemoDYNAMICs in Primary and Secondary Hypertension
NCT01742702 ·Status: RECRUITING
-
The Hypotensive Effect of Metformin in Hypertensive Patients.
NCT02072382 ·Status: UNKNOWN ·Phase: PHASE4
-
Comparison on Blood Pressure Effect of an Equivalent Sodium Intake, With Different Nature, for Hypertensive Subjects
NCT05108402 ·Status: UNKNOWN ·Phase: NA
-
Endothelial Function as a Marker for Blood Pressure Control Among Hypertensive Diabetic Patients
NCT00337038 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Effect of High Blood Pressure and Antihypertensive Treatment on Brain Functioning in Children
NCT00178490 ·Status: COMPLETED ·Phase: PHASE1
-
The Blood Pressure and Metabolic Effects of Nebivolol in Hypertensive Patients With Impaired Glucose Tolerance or Impaired Fasting Glucose
NCT00673790 ·Status: COMPLETED ·Phase: PHASE4
-
Central Hemodynamic and Sodium Urinary
NCT03932422 ·Status: UNKNOWN
-
Effects of the Dietary Approaches to Stop Hypertension(DASH) Sodium-restricted Diet in Diastolic Heart Failure
NCT00939640 ·Status: COMPLETED ·Phase: NA
-
Management of Hypertension and Multiple Risk Factors to Enhance Cardiovascular Health
NCT02972619 ·Status: UNKNOWN ·Phase: NA
-
Genetic Architecture of Natriuretic Peptides and Blood Pressure Response
NCT07118592 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Vascular Effects of Dietary Salt in Humans With Salt-Resistant Blood Pressure
NCT03424993 ·Status: COMPLETED ·Phase: PHASE4
-
Pharmacodynamic Effects of Sacubitril/Valsartan on Natriuretic Peptides, Angiotensin and Neprilysin
NCT03553303 ·Status: UNKNOWN ·Phase: PHASE4
-
Influence of Sodium Intake on Left Ventricular-arterial Coupling
NCT01965236 ·Status: TERMINATED ·Phase: NA
-
Dietary Approaches to Stop Hypertension in 'Diastolic' Heart Failure 2 (DASH-DHF 2)
NCT01942395 ·Status: TERMINATED ·Phase: NA
-
Food and Salt Handling in Diuresis
NCT04526340 ·Status: COMPLETED ·Phase: NA
-
Timing of Sodium Intake and Nocturnal Sodium Excretion and Blood Pressure in Obese African Americans
NCT04021355 ·Status: COMPLETED ·Phase: NA