Camrelizumab Combined With Apatinib 、XELOX 、RFA in the Treatment of Liver Metastases of Colorectal Cancer
NCT04202978 · Status: UNKNOWN · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 23
Last updated 2020-04-16
Summary
To evaluate the safety of karillizumab combined with apatinib mesylate, XELOX and radiofrequency ablation
Conditions
- Hepatic Metastasis of Colorectal Cancer
Interventions
- DRUG
-
Camrelizumab
Camrelizumab :200mg intravenous injection d1 q3w
- DRUG
-
Apatinib Mesylate
Apatinib:250mg/d P.O ,qd ,3weeks
- DRUG
-
capecitabine:850mg/m2 P.O ,bid ,d1-d14
- DRUG
-
oxaliplatin:130mg/m2 intravenous injection d1 q3w
- RADIATION
-
radiofrequency ablation
radiofrequency ablation:between first cycle and second cycle percutaneous
Sponsors & Collaborators
-
Zhongshan Hospital Xiamen University
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-03-01
- Primary Completion
- 2021-03-01
- Completion
- 2021-11-01
Countries
- China
Study Locations
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