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Acute and Chronic Inflammatory Disease, Lifestyle and Treatment Response

NCT04193020 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 300

Last updated 2021-04-20

No results posted yet for this study

Summary

Acute and chronic inflammatory eye diseases are difficult to diagnose and maintain quiescent with therapy. Proposed study is aimed to find on the one hand, novel factors for recurrence of the disease or remission of inflammation and evaluation of the impact of lifestyle and known factors on the other.

Each patient is treated in accordance to the best of medical knowledge and guidelines for each disease.

This prospective cohort study will enroll uveitic patients to the steroid only group (SG), combined (steroid and adjuvant drug) group (CG) or bilogic therapy group (BTG).

At baseline, patient data are recorded using patient-reported outcome measures and clinical assessments (ophthalomology) on disease activity (clinical scales), quality of life, and lifestyle together with registry data on comorbidity and medication. During follow-up evaluation of a successful treatment outcome response will be based on clinical scales and most frequently used primary endpoints; the major outcome of the analyses will be to detect differences in treatment outcome between patients in different treatment group.

Conditions

  • Uveitis

Interventions

OTHER

Surveillance card

Surveillance card and additional examination to find novel markers and better assess the existing ones

Sponsors & Collaborators

  • Wrocław University of Science and Technology

    collaborator OTHER

  • Wroclaw Medical University

    lead OTHER

Principal Investigators

  • Marta Misiuk-Hojło, Professor · Medical University of Wrocław

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-01-01
Primary Completion
2025-01-01
Completion
2026-01-01

Countries

  • Poland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04193020 on ClinicalTrials.gov