Resiliency in Older Adults Undergoing Bone Marrow Transplant
NCT04188678 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 126
Last updated 2025-10-27
Summary
The objective of this research is to measure certain indicators of resiliency to better understand which participants who are over 60 years old will respond more positively to bone marrow transplant. This research is being done to determine if there are traits that make recipients more likely to bounce back following allogeneic bone marrow transplant (BMT).
Conditions
- Leukemia
- Lymphoma
- Blood Cancer
- Myelodysplastic Syndrome
- Acute Myelogenous Leukemia
- Non-Hodgkins Lymphoma
Interventions
- OTHER
-
Bone Marrow Transplant (BMT)
Bone marrow transplantation will be conducted according to the investigators' institution's standard of care, or else according to research protocol (if applicable).Study visits that include the performance of assessments will occur prior to the start of conditioning chemotherapy and at 1 month and 6 months post-BMT. All dates are +/- 7 days. The initial study visit will take place during standard of care pre-transplant evaluations, which typically span 3-4 days. The post-BMT visits will take place before or after regularly-scheduled BMT follow up.
Sponsors & Collaborators
-
National Institutes of Health (NIH)
collaborator NIH -
National Institute on Aging (NIA)
collaborator NIH -
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
lead OTHER
Principal Investigators
-
Philip Imus, MD · Johns Hopkins University
Eligibility
- Min Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-09-28
- Primary Completion
- 2025-09-30
- Completion
- 2025-09-30
Countries
- United States
Study Locations
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