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Hemodynamic Responses to Cardio-respiratory Events in Preterm Infants

NCT04184245 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 42

Last updated 2020-01-29

No results posted yet for this study

Summary

Intermittent episodes of hypoxemia and/or bradycardia, also defined as cardio-respiratory events (CRE) are very frequent in preterm infants and may result in transient hypoxia and hypoperfusion of target organs, with possible clinical implications. The hemodynamic instability that characterizes the first 72 hours of life, also called as transitional period, place preterm infants at high risk of complications and may contribute to enhance fluctuations in end-organ perfusion and oxygenation induced by CRE. In this study we aimed to explore cardiovascular and cerebrovascular changes determined by different CRE types in preterm infants during the transitional period.

Conditions

  • Apnea of Prematurity
  • Preterm Birth
  • Patent Ductus Arteriosus
  • Hypoxia, Brain
  • Cardiac Output, Low
  • Bradycardia Neonatal
  • Hypoxia Neonatal

Sponsors & Collaborators

  • IRCCS Azienda Ospedaliero-Universitaria di Bologna

    lead OTHER

Principal Investigators

  • Luigi Corvaglia, MD · S. Orsola-Malpighi University Hospital, Bologna, Italy

Eligibility

Min Age
1 Day
Max Age
3 Days
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-02-22
Primary Completion
2019-12-31
Completion
2020-01-03

Countries

  • Italy

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04184245 on ClinicalTrials.gov