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Evaluation of Medical Conditions Associated With Zika Virus Infection in Managua, Nicaragua

NCT04182685 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 410

Last updated 2024-12-04

No results posted yet for this study

Summary

Zika virus (ZIKV) infection spread throughout the Americas with devastating consequences. Recent limited evidence suggests the potential for neurological effects associated with postnatally acquired ZIKV infection in humans; however, the impact on children is unknown. The researchers will conduct a longitudinal study of approximately 450 Nicaraguan children who were ages 2-12 in 2016 to evaluate the presence and persistence of neurological symptoms associated with ZIKV infection and to test whether ZIKV-infected children are at greater risk for developing neurological outcomes compared to uninfected children.

Conditions

  • Zika Virus

Sponsors & Collaborators

  • Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

    collaborator NIH

  • University of North Carolina, Chapel Hill

    collaborator OTHER

  • Sustainable Sciences Institute (Managua, Nicaragua)

    collaborator UNKNOWN

  • Ministry of Health Nicaragua

    collaborator UNKNOWN

  • RTI International

    lead OTHER

Principal Investigators

  • Jill F. Lebov, PhD · RTI International

Eligibility

Min Age
5 Years
Max Age
15 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-10-01
Primary Completion
2020-12-31
Completion
2020-12-31

Countries

  • Nicaragua

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04182685 on ClinicalTrials.gov