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Effectiveness of Rotavirus Immunization in Nicaragua

NCT01133808 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 667

Last updated 2011-09-09

No results posted yet for this study

Summary

The purpose of the investigators study is to compare the rates of childhood diarrhea at the community level before and after the rotavirus vaccination program in León, Nicaragua. From preliminary studies, the investigators anticipate about a 28% reduction in diarrhea following the vaccination program among children who received the vaccine, and a smaller reduction in diarrhea among children who did not receive the vaccine, due to the effects of "herd immunity". In addition, the investigators will collect stool samples from children who develop diarrhea in order determine the etiology of childhood diarrhea in the post-rotavirus immunization era.

Conditions

Sponsors & Collaborators

  • Merck Sharp & Dohme LLC

    collaborator INDUSTRY

  • Thrasher Research Fund

    collaborator OTHER

  • Fogarty International Center of the National Institute of Health

    collaborator NIH

  • Sylvia Becker-Dreps

    lead OTHER

Principal Investigators

  • Sylvia Becker-Dreps, MD · University of North Carolina, Chapel Hill

Eligibility

Max Age
5 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-01-31
Primary Completion
2011-01-31
Completion
2011-01-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01133808 on ClinicalTrials.gov