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Hyperinflation Respiratory Therapies in Cardiac Surgery Patients

NCT04164173 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 324

Last updated 2025-11-04

No results posted yet for this study

Summary

The purpose of this prospective randomized clinical trial is to evaluate three different types of hyperinflation respiratory therapies, Intermittent Positive Pressure Breathing (IPPB), Intermittent positive end expiratory pressure (EzPAP), Metaneb. Investigators will examine which hyperinflation therapy provides better lung expansion and may improve lung recovery after surgery.

Conditions

  • Pulmonary Disease
  • Postoperative Complications

Interventions

DEVICE

EzPAP

Patient will receive 10 min EzPAP 4 times daily

DEVICE

Metaneb

Patient will receive 10 min Metaneb 4 times daily

DEVICE

Intermittent Positive Pressure Breathing (IPPB)

Patient will receive 10 min IPPB 4 times daily

Sponsors & Collaborators

  • University of Texas Southwestern Medical Center

    lead OTHER

Principal Investigators

  • Jaffer Odeh, MD · UT Southwestern Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-06-15
Primary Completion
2028-08-01
Completion
2028-12-31
FDA Device
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04164173 on ClinicalTrials.gov