Precision-Panc Master Protocol: Personalising Treatment for Pancreatic Cancer
NCT04161417 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 2500
Last updated 2024-02-08
Summary
The Precision-Panc Master Protocol is a "portal" protocol for patients with known or suspected pancreatic cancer to be accrued through multiple centres in the UK, with the option of being subsequently enrolled into PRIMUS (Pancreatic canceR Individualised Multi-arm Umbrella Studies) examining different treatment regimens and/or biomarker development. Eligible patients will undergo tumour biopsy and blood collection prospectively for molecular profiling at a central laboratory and the results may be used to inform enrolment to PRIMUS studies.
Conditions
- Neoplasms Pancreatic
Interventions
- OTHER
-
Patients with suspected or confirmed pancreatic cancer will be be asked to provide biopsy material for molecular profiling
Patients with suspected or confirmed pancreatic cancer will be be asked to provide biopsy material for molecular profiling. This will enable patient enrolment into a currently available PRIMUS study
Sponsors & Collaborators
- collaborator OTHER
-
NHS Greater Glasgow and Clyde
collaborator OTHER -
Judith Dixon-Hughes
lead OTHER
Principal Investigators
-
David Chang · University of Glasgow
-
Juan Valle · University of Manchester
Study Design
- Allocation
- NA
- Purpose
- SCREENING
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 16 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-11-28
- Primary Completion
- 2025-12-31
- Completion
- 2025-12-31
Countries
- United Kingdom
Study Locations
More Related Trials
-
RNA Precision Oncology in Advanced Pancreatic Cancer
NCT04476537 ·Status: TERMINATED ·Phase: NA
-
Pembrolizumab Plus Chemotherapy in 1st Line Treatment of Pancreatic Cancer
NCT04447092 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Prospective Cohort Study of Pancreatic Cancer Patients Treated With Proton Beam Therapy
NCT04466189 ·Status: ENROLLING_BY_INVITATION
-
PROACTIVE: Surgical Resection Outcomes in Locally Advanced and Unresectable Pancreatic Cancer After Neoadjuvant Chemotherapy
NCT06132087 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
A Study of Therapy Selected by Molecular/Metabolic Profiling in Patients With Previously Treated Metastatic Pancreatic Cancer
NCT01196247 ·Status: COMPLETED ·Phase: PHASE2
-
Verification of Predictive Biomarkers for Pancreatic Cancer Treatment Using Multicenter Liquid Biopsy
NCT04241367 ·Status: COMPLETED
-
New and Emerging Therapies for the Treatment of Resectable, Borderline Resectable, or Locally Advanced Pancreatic Cancer, PIONEER-Panc Study
NCT04481204 ·Status: WITHDRAWN ·Phase: PHASE2
-
Pancreas Cancer: Molecular Profiling as a Guide to Therapy Before and After Surgery ("Personalized Medicine")
NCT01726582 ·Status: COMPLETED ·Phase: PHASE2
-
Multi-agent Low Dose Chemotherapy GAX-CI Followed by Olaparib and Pembro in Metastatic Pancreatic Ductal Cancer.
NCT04753879 ·Status: RECRUITING ·Phase: PHASE2
-
Protocol to Permit the Acquisition of Circulating Tumor Material in Pancreatic Diseases
NCT02471170 ·Status: ENROLLING_BY_INVITATION
-
A Prospective Study of Liquid Biopsy for Pancreatic Cancer Early Detection
NCT06166147 ·Status: RECRUITING
-
First-in-human Study of the Theranostic Pair [68Ga]Ga DOTA-5G and [177Lu]Lu DOTA-ABM-5G in Pancreatic Cancer
NCT04665947 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
PREOPANC-4 Implementation Program for Locally Advanced Pancreatic Cancer
NCT05524090 ·Status: RECRUITING
-
Biomarkers Study in Pancreatic Cancer
NCT01666184 ·Status: UNKNOWN
-
Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations
NCT06998940 ·Status: RECRUITING ·Phase: PHASE3
-
A Real-World Study of Precision Treatment for Advanced Cholangiocarcinoma Based on Molecular Subtyping
NCT07164703 ·Status: NOT_YET_RECRUITING
-
Role of Perfusion CT in Pancreatic Cancer
NCT01703650 ·Status: UNKNOWN
-
AG-013736 In Combination With Gemcitabine Versus Gemcitabine Alone For Patients With Metastatic Pancreatic Cancer
NCT00219557 ·Status: COMPLETED ·Phase: PHASE2
-
Pancreatic Cancer Screening for At-risk Individuals
NCT05006131 ·Status: RECRUITING
-
In Vitro Organoid Drug Sensitivity-Guided Treatment for Metastatic Pancreatic and Gastric Cancer
NCT05842187 ·Status: UNKNOWN ·Phase: NA
-
Panitumumab, Chemotherapy, and External-Beam Radiation Therapy in Treating Patients With Locally Advanced Pancreatic Cancer That Cannot be Removed by Surgery
NCT00601627 ·Status: COMPLETED ·Phase: PHASE2
-
Observational Study of Quality of Live in Patients With Metastatic Pancreatic Cancer
NCT02342847 ·Status: COMPLETED
-
Pancreatic Adenocarcinoma Gene Environment Risk Study
NCT00912717 ·Status: RECRUITING
-
SERum-bank for PANcreatic Cancer
NCT04374175 ·Status: RECRUITING
-
Dinaciclib and Akt Inhibitor MK2206 in Treating Patients With Pancreatic Cancer That Cannot Be Removed by Surgery
NCT01783171 ·Status: COMPLETED ·Phase: PHASE1