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The Cerebral-Coronary Connection (C3) Study

NCT04131075 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2020-01-06

No results posted yet for this study

Summary

This is a prospective cohort blinded study with the aim to investigate the prevalence and clinical impact of coronary microcirculatory dysfunction (CMD) in patients with ischemic heart disease, and its association with cerebral small vessel disease (CSVD) and depressive disorders. In addition, CMD and CSVD linkage to systemic inflammation and endothelial function will also be investigated.

Conditions

  • Ischemic Heart Disease
  • Microvascular Coronary Artery Disease
  • Depression
  • Endothelial Dysfunction
  • Inflammation

Interventions

PROCEDURE

Coronary Angiography and Multimodal Coronary Physiology Study (FFR, CFR, HMR)

Coronary Angiography according to clinical indication and Multimodal Coronary Physiology Study (FFR, CFR, HMR) for functional assessment of intermediate coronary lesions

Sponsors & Collaborators

  • Hospital San Carlos, Madrid

    collaborator OTHER

  • Instituto de Salud Carlos III

    lead OTHER_GOV

Principal Investigators

  • Javier Escaned, MD, PhD · Instituto Carlos III. Hospital Clínico San Carlos.

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-03-01
Primary Completion
2019-12-31
Completion
2020-03-31

Countries

  • Spain

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04131075 on ClinicalTrials.gov