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Impact of Adrenal IncidenTalomas and Possible Autonomous Cortisol Secretion on Cardiovascular and Metabolic Alterations

NCT04127552 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 68

Last updated 2025-03-28

No results posted yet for this study

Summary

The investigators hypothesize that cardiovascular and metabolic alterations can occur in patients with adrenal adenomas and possible Autonomous Cortisol Secretion (pACS). Investigators hypothesize that adrenalectomy in selected patients, following the 2016 European Congress of Endocrinology (ECE) guidelines, can improve metabolic parameters and cardiovascular risks and features.

Conditions

  • Adrenal Incidentaloma
  • Hypercortisolism
  • Adrenal Tumor

Interventions

PROCEDURE

Adrenalectomy

Adrenalectomy according to 2016 ESE guidelines

Sponsors & Collaborators

  • University of Roma La Sapienza

    lead OTHER

Principal Investigators

  • Andrea M Isidori, MD, PHD · Sapienza

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-01-02
Primary Completion
2025-12-31
Completion
2025-12-31

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04127552 on ClinicalTrials.gov