Genomic and Epigenomic Alterations After Cancer Treatment in Pregnancy
NCT04125446 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 150
Last updated 2022-09-27
Summary
The investigators want to obtain a fundamental understanding if and which chemotherapeutic agents used for treating cancer during pregnancy are associated with placental and/or offspring (epi)genetic changes, potentially causing FGR and childhood/adult diseases later in life.
Conditions
- Cancer
- Pregnancy
Sponsors & Collaborators
-
University Hospital, Antwerp
collaborator OTHER -
University Hospital, Ghent
collaborator OTHER -
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
collaborator OTHER -
University Hospital, Gasthuisberg
lead OTHER
Principal Investigators
-
Frédéric Amant, MD,PhD · Universitaire Ziekenhuizen KU Leuven
Eligibility
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2019-10-15
- Primary Completion
- 2023-12-31
- Completion
- 2023-12-31
Countries
- Belgium
Study Locations
More Related Trials
-
Evaluation of Pre-dose and Post-dose Anti-factor Xa Levels With Enoxaparin Use During Pregnancy
NCT00319176 ·Status: COMPLETED
-
Collection of Outcomes Data for Pregnant Patients With Cancer
NCT00507572 ·Status: TERMINATED
-
Epigenomic Dysregulation in Preeclampsia-Associated Chronic Hypertension
NCT01682304 ·Status: COMPLETED
-
Obstetric Complications in Women Who Smoke During Pregnancy
NCT01758276 ·Status: UNKNOWN
-
Angiotensinogen Variants and Adverse Pregnancy Outcomes
NCT00005400 ·Status: COMPLETED
-
Immunological and Cardiovascular Phenotyping of Oocyte-donation Pregnancies
NCT04731012 ·Status: RECRUITING
-
Environmental Factors and Embryonic Development Project
NCT04182503 ·Status: UNKNOWN
-
Early PrEgnancy Complications Testing
NCT04079361 ·Status: RECRUITING ·Phase: NA
-
Congenital Uterine Anomalies: Identifying Cancer Associations and Genetic and Environmental Factors to Improve Clinical Care
NCT04661072 ·Status: RECRUITING
-
Prevalence of Ambivalence Regarding Prenatal Testing
NCT00342069 ·Status: COMPLETED
-
The Levels of the Orexin, Galanin and aMSH and CART in Patients With Hyperemesis Gravidarum
NCT05446025 ·Status: COMPLETED
-
Evolocumab Pregnancy Exposure Registry
NCT02957604 ·Status: TERMINATED
-
Placental Growth and Adverse Pregnancy Outcomes
NCT01669525 ·Status: COMPLETED
-
Prenatal Genetic Diagnosis by Genomic Sequencing
NCT03936101 ·Status: COMPLETED
-
Mavacamten Pregnancy Surveillance Program
NCT05939700 ·Status: RECRUITING
-
Family Study on Preeclampsia
NCT00344162 ·Status: COMPLETED
-
A Study of Pregnancy Outcomes in Congenital Heart Disease
NCT06678256 ·Status: WITHDRAWN
-
X-Chromosome Inactivation Status and Premature Ovarian Failure
NCT00295087 ·Status: COMPLETED
-
Study to Evaluate the Safety of Repatha® in Pregnancy
NCT02906124 ·Status: TERMINATED
-
Transplacental Transfer of Drugs Used in Pregnant Women
NCT02622802 ·Status: COMPLETED ·Phase: NA
-
Non-invasive Placental Chromosome Exploration of Intrauterine Growth Restriction
NCT05023161 ·Status: RECRUITING
-
Risk Factors of Ectopic Pregnancy
NCT00194207 ·Status: COMPLETED
-
Angiogenic Factors in the Conservative Management of Gestational Hypertension
NCT06123377 ·Status: RECRUITING ·Phase: NA
-
NIH Intramural Research Program s Pregnancy Registry Protocol for Subjects and Their Partners
NCT04977466 ·Status: ENROLLING_BY_INVITATION
-
Prospective Study in Pregnant Women With Hypercoagulopathy
NCT00215969 ·Status: UNKNOWN