ALFAOMEGA Master Observational Trial
NCT04120935 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 3000
Last updated 2025-08-24
Summary
AlfaOmega has been designed to streamline the study of the co-evolutionary landscape between tumor and host cells in a cohort of CRC patients, with the aim of understanding how their outcomes can be significantly improved (e.g. reduction of their chance of recurrence and survival improval). This clinical resource for integrative clinical data and sample collection will allow the molecular story-telling of CRC metastatic spread along time and space and the selection of appropriate patients for experimentally-driven trials.
Conditions
Interventions
- OTHER
-
Observation
Prospective Observation of standard clinical practice.
Sponsors & Collaborators
-
IFOM ETS - The AIRC Institute of Molecular Oncology
lead OTHER
Principal Investigators
-
Silvia Marsoni, MD · IFOM ETS - The AIRC Institute of Molecular Oncology
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-10-15
- Primary Completion
- 2026-06-30
- Completion
- 2026-12-31
Countries
- Italy
- Spain
Study Locations
More Related Trials
-
CARE-CRC: Microbiome Insights and Correlations for Risk and Outcomes in Colorectal Cancer
NCT06734156 ·Status: RECRUITING
-
Living With Colorectal Cancer: Patient and Caregiver Experience
NCT03572101 ·Status: COMPLETED
-
Evaluation of Some Risk Factors Associated With Colorectal Cancer
NCT05170360 ·Status: UNKNOWN
-
A Comparative Study Between Early Onset Colorectal Cancer and Late Onset Colorectal Cancer Patients
NCT06326879 ·Status: RECRUITING
-
Predictors of Disease Recurrence After Curative Surgery for Stage I Colon Cancer
NCT05726188 ·Status: UNKNOWN
-
Early Detection of Treatment Failure in Metastatic Colorectal Cancer Patients
NCT05068531 ·Status: RECRUITING
-
The Immunoscore as a Prognostic Marker for Patients With a Colorectal Cancer
NCT01688232 ·Status: UNKNOWN
-
Personalized Medicine in Early Stage Colorectal Cancer: Organ Preservation and Immune Benefit
NCT06251726 ·Status: NOT_YET_RECRUITING
-
Intraoperative Flow Cytometry In Colorectal Cancer
NCT05261542 ·Status: COMPLETED
-
Should Colorectal Cancer Patients be Followed After Five Years? Study of Recurrence in a Population Cohort
NCT01904955 ·Status: COMPLETED
-
Combining Risk Factors and Faecal Immunochemical Testing in Colorectal Cancer Screening: a Randomized Controlled Trial
NCT04490551 ·Status: COMPLETED ·Phase: NA
-
Appropriateness of Colonoscopy Indication: an Evaluation of the Clinical and Economic Impact.
NCT06775951 ·Status: RECRUITING
-
LRP1 Methylation and Colon Cancer
NCT02786602 ·Status: COMPLETED
-
Molecular Profiling of Colorectal Cancer
NCT04863768 ·Status: UNKNOWN
-
Earlier Detection and Optimization of Treatment and Prognosis for Patients With Early-onset Colorectal Cancer
NCT06568679 ·Status: RECRUITING
-
Observational Cross-reactivity Study for Colorectal Cancer Diagnosis
NCT06889844 ·Status: RECRUITING
-
Artificial Intelligence-based Screening Models for Prevention and Early Detection of Colorectal Cancer
NCT06799793 ·Status: RECRUITING ·Phase: NA
-
FOcUs on Colorectal CAncer oUtcomes: Long-Term Study
NCT03965325 ·Status: COMPLETED
-
The Future Management of Patients With Neoplasms of the Gastro-intestinal Tract
NCT06728358 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
ColoCare Study - Colorectal Cancer Cohort
NCT02328677 ·Status: RECRUITING
-
The Colorectal Cancer Chemoprevention Acceleration and Improvement Platform (CRC-CHAMP) Study
NCT05402124 ·Status: UNKNOWN ·Phase: PHASE2
-
Exploring Participant Preference for Screening Methods and Experience Into Colorectal Cancer Screening Programme
NCT06696534 ·Status: RECRUITING ·Phase: NA
-
Circulating Tumor Cells and Neutrophils Count for Colorectal Metastatic Cancer
NCT05793775 ·Status: COMPLETED
-
Endomicrocancer: Confocal Endomicroscopy in Patients With High Risk of Colorectal Cancer
NCT01052376 ·Status: TERMINATED ·Phase: NA
-
Investigation of the Role of the Microbiome in the Pathogenesis of Colorectal Adenoma and Carcinoma
NCT02947607 ·Status: COMPLETED