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Biomarkers of Common Eye Diseases

NCT04101604 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 220

Last updated 2019-09-27

No results posted yet for this study

Summary

To identify biomarkers of common eye diseases based on single-cell sequencing technologies using PBMC samples. These diseases include uveitis, diabetic retinopathy, age-related macular degeneration and polypoid choroidal vasculopathy. Our study may provide new insight into the underlying mechanisms, and reveal novel predictors and intervention targets for the diagnosis, prognosis and treatment of these diseases.

Conditions

  • Uveitis
  • Diabetic Retinopathy
  • Age-related Macular Degeneration
  • Polypoidal Choroidal Vasculopathy
  • VKH Syndrome
  • Behçet Disease

Interventions

OTHER

Collection of blood samples

Collection of blood samples for DNA extraction and genetic characterization, and for identification of peripheral blood biomarkers using single-cell transcriptomics and mass cytometry.

Sponsors & Collaborators

  • Sun Yat-sen University

    lead OTHER

Principal Investigators

  • Yingfeng Zheng · Zhognshan Ophthalmic Center, Sun Yat-sen University

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-09-26
Primary Completion
2020-10-01
Completion
2021-10-01

Countries

  • China

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04101604 on ClinicalTrials.gov