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Effect of DNMT SNPs on DNA Methylation in Primary ITP

NCT04100876 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 90

Last updated 2019-09-24

No results posted yet for this study

Summary

* To compare global DNA methylation status between ITP patients and healthy subjects .
* To determine the effect of DNMT3A -448 G/A SNP variant A allele and DNMT3B -149C/T SNP variant T-allele on global DNA methylation in both ITP patients and healthy control subjects.

Conditions

  • Primary Immune Thrombocytopenia

Interventions

GENETIC

Global DNA methylation will be quantified in the DNA samples by colorimetry

Global DNA methylation will be quantified in the DNA samples by colorimetry

Sponsors & Collaborators

  • Assiut University

    lead OTHER

Principal Investigators

  • Heba A Abdel-Hafeez, Professor · Clinical Pathology Department in Assuit University Hospital

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-12-01
Primary Completion
2021-10-01
Completion
2021-12-01

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04100876 on ClinicalTrials.gov