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Osteoradionecrosis and PENTOCLO Protocol: Retrospective Study

NCT04097847 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 96

Last updated 2019-11-01

No results posted yet for this study

Summary

osteoradionecrosis (ORN) affects up to 30% of irradiated patients and can occur up to several decades after stopping treatment. Differents therapeutics exist but there is no consensus concerning the management of the maxillary ORN. The understanding of new pathological mechanisms opens the way to new therapeutic perspectives.

Conditions

  • Osteoradionecrosis of Jaw

Interventions

DRUG

Pentoxifylline-Tocopherol-Clodronate

the aim of this retrospective study is to analyze from patient records the impact of the PENTOCLO protocol on maxillofacial osteoradionecrosis at Brest Hospital University, France.

Sponsors & Collaborators

  • University Hospital, Brest

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-06-02
Primary Completion
2019-04-01
Completion
2019-04-01

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04097847 on ClinicalTrials.gov