Activity of Pre-Osteoclasts and Osteoclasts Over Time in Postmenopausal Women Treated With Denosumab or Zoledronic Acid
NCT03812367 · Status: WITHDRAWN · Type: OBSERVATIONAL
Last updated 2019-06-14
Summary
This study evaluates how patients treated with denosumab or zoledronic acid for osteoporosis may change the number of peripheral osteoclast precursors and osteoclast activity, and how that may be associated with changes in bone mass.
Conditions
- Osteoporosis, Postmenopausal
Sponsors & Collaborators
- collaborator INDUSTRY
-
University of California, Davis
lead OTHER
Principal Investigators
-
Nancy Lane, MD · University of California, Davis
Eligibility
- Min Age
- 50 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-01-01
- Primary Completion
- 2021-06-01
- Completion
- 2021-12-31
Countries
- United States
Study Locations
More Related Trials
-
Bisphosphonates for Prevention of Post-Denosumab Bone Loss
NCT03396315 ·Status: COMPLETED ·Phase: PHASE2
-
A Transiliac Crest Bone Histology and Histomorphometry Study in Postmenopausal Women With Low Bone Mass or Osteoporosis Previously Treated With Denosumab
NCT00887965 ·Status: COMPLETED ·Phase: PHASE2
-
Denosumab for Treating Periprosthetic Osteolysis.
NCT02299817 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study to Evaluate Denosumab in the Treatment of Postmenopausal Osteoporosis
NCT00089791 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy Study of Zoledronic Acid and Teriparatide Combination Therapy in Women With Osteoporosis
NCT00439244 ·Status: COMPLETED ·Phase: PHASE3
-
Romosozumab/Denosumab Study for Premenopausal IOP
NCT04800367 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Treatment With Zoledronic Acid Subsequent to Denosumab in Osteoporosis
NCT03087851 ·Status: COMPLETED ·Phase: PHASE4
-
Zoledronic Acid in the Prevention of Bone Loss in Postmenopausal Women With Osteopenia, 45 Years of Age and Older
NCT00132808 ·Status: COMPLETED ·Phase: PHASE3
-
Effects of Zoledronic Acid and Raloxifene on Bone Turnover Markers in Postmenopausal Women With Low Bone Mineral Density
NCT00431444 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy and Safety of Odanacatib in Postmenopausal Women Previously Treated With Oral Bisphosphonate (MK-0822-076)
NCT01803607 ·Status: TERMINATED ·Phase: PHASE3
-
Denosumab vs Zoledronate After Lumbar Fusion
NCT05638399 ·Status: UNKNOWN ·Phase: PHASE3
-
Effect of Denosumab on Inflammatory Osteolytic Lesion Activity in Total Hip Arthroplasty
NCT01358669 ·Status: COMPLETED ·Phase: PHASE2
-
A Randomized, Double-Blind Study to Compare the Efficacy of Treatment With Denosumab Versus Alendronate Sodium in Postmenopausal Women With Low Bone Mineral Density.
NCT00330460 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Evaluate the Safety and Efficacy of Denosumab and Ibandronate in Postmenopausal Women Sub-Optimally Treated With Daily or Weekly Bisphosphonates
NCT00936897 ·Status: COMPLETED ·Phase: PHASE3
-
Effect of Vitamin D and Denosumab on Bone Remodelling in Women With Postmenopausal Osteoporosis
NCT05372224 ·Status: COMPLETED ·Phase: NA
-
Treatment With Zoledronate Subsequent to Denosumab in Osteoporosis 2 (ZOLARMAB2)
NCT05655013 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE4
-
Osteoclast Inhibition and Bone Formation
NCT02554695 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
A Randomized, Double-blind, Placebo-controlled, Dose Response Study of AMG 162 (Denosumab) in Japanese Postmenopausal Osteoporotic Subjects
NCT00306189 ·Status: COMPLETED ·Phase: PHASE2
-
Comparative Effect of Zoledronic Acid Versus Denosumab on Serum Sclerostin of Postmenopausal Women With Low Bone Mass
NCT01572545 ·Status: COMPLETED ·Phase: NA
-
Denosumab Fracture Intervention Randomized Placebo Controlled Trial in Japanese Patients With Osteoporosis
NCT00680953 ·Status: COMPLETED ·Phase: PHASE3
-
3 yr Efficacy & Safety Study of Zoledronic Acid in Post-menopausal Women With Osteoporosis Treated With Zol Acid for 6 Yrs
NCT00718861 ·Status: COMPLETED ·Phase: PHASE3
-
Denosumab vs Zoledronic Acid and Osteoporotic Compression Fracture
NCT05106517 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Effects of Teriparatide or Zoledronic Acid Treatment on Bone in Postmenopausal Osteoporotic Women
NCT00927186 ·Status: COMPLETED ·Phase: PHASE4
-
StrAtegies For Zoledronic Acid Post-dEnosumab Discontinuation in Postmenopausal oSTeoporosis
NCT06767150 ·Status: RECRUITING ·Phase: PHASE4
-
Double-blind Extension of HORIZON Pivotal Fracture Trial (Zoledronic Acid in the Treatment of Postmenopausal Osteoporosis)
NCT00145327 ·Status: COMPLETED ·Phase: PHASE3