Think Dry: Optimalisation of Diagnostic Process of Urinary Incontinence in Older People

Summary

Urinary incontinence is an increasing medical and socio-economical problem. 44% of the elderly (\>65 years) women and 28% of the elderly men suffer from unwilling urine loss. Moreover, this percentages increase with age. Incontinence is a problem with multiple physical, psychological, and financial effects. In addition incontinence has a important impact on the family and healthcare professionals surrounding the elderly.

The problem of urinary incontinence is complex and multifactorial. Moreover, diagnostic guidelines are inconsistent leading to a high amount of technical interventions to diagnose and to specify the type of incontinence.

Aim of this study is to create a short form of necessary technical investigations to diagnose and evaluate urinary incontinence.

Conditions

• Incontinence, Urge
• Incontinence Stress
• Incontinence, Daytime Urinary
• Incontinence, Nighttime Urinary

Interventions

DIAGNOSTIC_TEST

Blood Sample

A sober blood sample is taken to observe the following parameters: creatinin, ureum, sodium, potassium, osmolality, HDL cholesterol, LDL cholesterol, triglycerides)

DIAGNOSTIC_TEST

Renal Function Profile

A Renal Function Profile is a 24 hour-urine collection in which urine samples are collected at fixed time points every 3 hours, starting 3 hours after the first morning void. Daytime samples were taken at 10:00-11:30 (U1), 13:00-15:30 (U2), 16:00-17:30 (U3), 19:00-20:30 (U4), and 22:00-23:30 (U5). The nighttime samples were taken at 1:00-2:30 (U6), 4:00-5:30 (U7) and 7:00-8:30 (U8). The volume of each sample, and of each micturition in between, was noted to calculate the 24h, daytime and nighttime urine volume and diuresis rate.

DIAGNOSTIC_TEST

Frequency Volume Chart

Every patient complets a frequency volume chart during 24 of 72 hours

DIAGNOSTIC_TEST

Cystometry

This technique provide the most precise measurement of bladder and urethral sphincter behaviour during bladder filling and during voiding.

DIAGNOSTIC_TEST

Questionaires

Patients have to fulfill the following questionaires * ICIQ-Fluts for female participants or ICIQ-Mluts for male participants * TILBURG FRAILTY INDICATOR * SF-36 Quality of Life score * N- QOL

DIAGNOSTIC_TEST

Flow rate measurement + Observation of the post-void residual urine volume

A measurement of the urinary flow rate is observed to collect the maximum Q/s. Afterwards an observation of the PVR is done using ultrasound.

DIAGNOSTIC_TEST

Clinical Examination

Clinical examination of the genital region. For women, coeles are described using the POPQ

Sponsors & Collaborators

• University Hospital, Ghent

  lead OTHER

Eligibility

Min Age

65 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2014-01-01

Primary Completion

2024-08-01

Completion

2024-08-01

Countries

• Belgium

Study Locations