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Effect of Depletive Lumbar Puncture on Lower Urinary Tract Dysfunction in iNPH

NCT03877107 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2019-03-19

No results posted yet for this study

Summary

Lower urinary tract dysfunction in normal pressure hydrocephalus has received little attention from the scientific community. Urinary symptoms in normal pressure hydrocephalus are mainly represented by overactive bladder, which is a significant burden for the concerned patients. A harmonization of neuro-urological practices in the pre-therapeutic evaluation of patients suffering from normal pressure hydrocephalus is necessary.

The investigators conducted a bicentric prospective study aiming to evaluate the effect of depletive lumbar puncture on urinary symptoms in iNPH.

The secondary objective was to evaluate, in the same participants previously diagnosed, the effect of cerebrospinal fluid shunt surgery on urinary symptoms.

Conditions

  • Normal Pressure Hydrocephalus

Interventions

DIAGNOSTIC_TEST

Urinary symptoms profile questionnaire

Validated questionnaire (international) with validated french translation, before and after lumbar puncture, and after surgery if surgery is realized

DIAGNOSTIC_TEST

Micturition calendar

Micturition calendar on 2 consecutive days, before and after lumbar puncture, and after surgery if surgery is realized

Sponsors & Collaborators

  • EssaiClinique_PL-HPN

    lead OTHER

Principal Investigators

  • Jean Alexandre LONG, MD PHD · University Hospital, Grenoble

Study Design

Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-03-13
Primary Completion
2020-09-01
Completion
2021-03-01

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03877107 on ClinicalTrials.gov