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XIST Gene Deletion in Breast Cancer Therapy

NCT04093609 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 1

Last updated 2019-09-18

No results posted yet for this study

Summary

Very little is known about the role of X-inactive specific transcript RNA in human breast cancer and in regulating different response to therapy .

the relation between the breast cancer predisposing gene BRCA1 \& X-inactive specific transcript RNA has been investigated but still controversial.

Loss of X chromosome inactivation (XCI) is observed in breast cancer . Other studies sheds light on a possible mechanism of breast carcinogenesis mediated by XIST misbehaviour.

Conditions

Interventions

GENETIC

XIST gene deletion

detection of XIST gene deletion by fluorescence in situ hybridization

Sponsors & Collaborators

  • Assiut University

    lead OTHER

Eligibility

Min Age
20 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-03-01
Primary Completion
2021-03-01
Completion
2022-03-01

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04093609 on ClinicalTrials.gov