The Efficacy Of Complete Mesocolic Excision With Central Vessel Ligation Technique On Lymph Nodes And Safety Margins Compared With Conventional Surgery For Colon Cancer Treatment
NCT04079946 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40
Last updated 2019-09-06
Summary
Cancer Colon is one of the major public health problems worldwide. Complete eradication of the tumor with no recurrence or residual masses is a challenge which faces all the surgeons and medical staff all over the world. A lot of techniques were used to ensure 100 % eradication of the tumor and to cure the patients from cancer. Total Mesocolic Excision with Central Vessel Ligation is one of the recent techniques used for colon cancer surgeries. Here in the research the investigators answer the question of how this technique is superior and more beneficial in complete eradication of the tumor than the conventional surgery for colon cancer
Conditions
- Cancer Colon
Interventions
- PROCEDURE
-
Total Mesocolic Excision with Central Vessel Ligation
sharp dissection of the anatomical layers and the dissection of the visceral plane from the parietal one . In addition a central division of the feeding arteries at their origins is performed at the level of superior mesenteric artery for tumors of the right colon and at the level of inferior mesenteric artery or the aorta for tumors of the left colon .this allows for removal of the maximum number of lymph nodes possible.
- PROCEDURE
-
conventional surgery of cancer colon
removal of the tumor with no ligation of the vessel centrally or removal of the whole mesocolon
Sponsors & Collaborators
-
Assiut University
lead OTHER
Principal Investigators
-
Mostafa A. Hassanein, professor · Assiut University
-
Mohamed B. Kotb, profeesor · Assiut University
-
Mahmoud T. Ahmed, lecturer · Assiut University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-10-01
- Primary Completion
- 2020-12-31
- Completion
- 2021-06-01
More Related Trials
-
The Comparison Between Traditional Laparoscopy-assisted Surgery and NOSES in Radical Resection of Colorectal Cancer
NCT03470142 ·Status: UNKNOWN ·Phase: NA
-
Open Versus Laparoscopic Right Hemicolectomy for Right Colon Cancer
NCT04434508 ·Status: COMPLETED ·Phase: NA
-
Influence of the Surgical Technique Used for Colectomies on the Concentration of Circulating Tumor DNA and the Presence of Circulating Tumor Cells: Comparison of the "no Touch" Technic With Either First Clamping of the Mesenteric Vessels or First Mobilization of the Tumor Followed by Clamping.
NCT03809403 ·Status: UNKNOWN
-
Outcomes of Side-to-end Versus End-to-end Colorectal Anastomosis in Non-emergent Sigmoid and Rectal Cancers: Randomized Controlled Clinical Trial
NCT04694521 ·Status: COMPLETED ·Phase: NA
-
Combined Medial and Caudal Approach for Right Hemicolectomy
NCT05128708 ·Status: COMPLETED ·Phase: NA
-
Intracorporeal vs. Extracorporeal Anastomosis in Patients Undergoing Laparoscopic Right Hemicolectomy for Colonic Cancer
NCT05039762 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Comparison Between Results of 2 Laparoscopic Surgical Procedures in Operable Colon Cancer Cases in Upper Egypt
NCT05421702 ·Status: COMPLETED ·Phase: NA
-
Oncologic Outcomes of Single-incision Versus Conventional Laparoscopic Surgery for Colorectal Cancer
NCT04527861 ·Status: RECRUITING ·Phase: NA
-
Comparison of Cold and Hot Loop Resection Techniques for the Removal of Medium-sized Benign Colon Tumors
NCT07041255 ·Status: RECRUITING ·Phase: NA
-
Laparoscopic Right Hemicolectomy With Transrectal Specimen Extraction for Colon Cancer
NCT06362902 ·Status: RECRUITING ·Phase: NA
-
Laparoscopic Versus Open Right Hemicolectomy Within ERAS in Right-sided Colon Cancer
NCT02944188 ·Status: COMPLETED ·Phase: NA
-
Laparoscopic Complete Mesocolic Excision on Colon Cancer
NCT01628250 ·Status: COMPLETED ·Phase: NA
-
Laparoscopic Versus Open Right Colectomy for Right Colon Cancer
NCT05713903 ·Status: RECRUITING ·Phase: NA
-
Randomized Controlled Trial Between Laparoscopic and Open Surgery in Transverse and Descending Colon Cancer Patients
NCT01861691 ·Status: UNKNOWN ·Phase: PHASE2
-
Evaluation of the Extraction-site, - Midline Incision vs Off-midline Incision-
NCT02253303 ·Status: UNKNOWN ·Phase: NA
-
Intracorporeal Versus Extracorporeal Anastomotic After Laparoscopic Right Colectomy
NCT05493033 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Safety and Efficacy of Reduced-port Laparoscopic Surgery for Patients Of Colon and Upper Rectal Cancer
NCT05953662 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Laparoscopic Surgery Equivalent to Open Surgery in Right Colon Cancer Surgery?
NCT01772407 ·Status: COMPLETED
-
Robotic vs Laparoscopic D3-D4 Lymphadenectomy for Colorectal Cancer
NCT05961423 ·Status: UNKNOWN ·Phase: NA
-
Prospective Registration Study of Robtic Laparoscopy Versus Laparoscopy Assisted Colon Cancer Surgery
NCT04843189 ·Status: UNKNOWN
-
Open Versus Laparoscopic Complete Mesocolic Excision for Locally Advanced Colon Cancer
NCT02682589 ·Status: UNKNOWN ·Phase: PHASE3
-
INtracorporeal Versus EXTracorpoREal anastoMOsis After Laparoscopic Right Colectomy for Cancer
NCT01679756 ·Status: UNKNOWN ·Phase: NA
-
Non-microradical Resection Margin as a Predictor for Recurrence After Complete Mesocolic Excision
NCT04395534 ·Status: COMPLETED
-
Comparison of NOSES and Conventional Laparoscopic Surgery in Colorectal Cancer
NCT04559087 ·Status: UNKNOWN ·Phase: NA
-
Intracorporeal Versus Extracorporeal Anastomosis In Laparoscopic Right Colon Resection
NCT05077358 ·Status: UNKNOWN ·Phase: NA