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Mechanisms of Exercise Intolerance in Heart Failure With Preserved Ejection Fraction

NCT04068844 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 93

Last updated 2025-01-01

No results posted yet for this study

Summary

The global objective of this study is to determine the mechanisms of exercise intolerance and dyspnea on exertion (DOE) in patients with HFpEF and based on this pathophysiology, test whether specific exercise training programs (whole body vs single leg) will result in improved exercise tolerance.

Conditions

  • Heart Failure, Diastolic

Interventions

BEHAVIORAL

Exercise training

Exercise training, either whole body or isolated single leg

Sponsors & Collaborators

  • The University of Texas at Arlington

    collaborator OTHER

  • University of Texas Southwestern Medical Center

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
FACTORIAL

Eligibility

Min Age
60 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-08-01
Primary Completion
2025-08-01
Completion
2025-12-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04068844 on ClinicalTrials.gov