Effects of Netarsudil and Timolol on Retinal Blood Vessel Density and Visual Acuity
NCT04064918 · Status: WITHDRAWN · Phase: NA · Type: INTERVENTIONAL
Last updated 2022-03-31
Summary
The purpose of this research study is to compare the effect of Netarsudil and Timolol on eye pressure and blood vessels of the back of the eye.
Conditions
- OAG - Open-Angle Glaucoma
- OHT - Ocular Hypertension
Interventions
- OTHER
-
Netarsudil 0.02% QD
This is a randomized, single-center, investigator-masked, 2-period, 8-week treatment study with washout and crossover between treatment periods. There will be 2 treatments in this study: netarsudil 0.02% QD and timolol maleate 0.5% BID.
- OTHER
-
Timolol maleate 0.5% BID
This is a randomized, single-center, investigator-masked, 2-period, 8-week treatment study with washout and crossover between treatment periods. There will be 2 treatments in this study: netarsudil 0.02% QD and timolol maleate 0.5% BID.
Sponsors & Collaborators
-
Aerie Pharmaceuticals
collaborator INDUSTRY -
University of California, San Diego
lead OTHER
Principal Investigators
-
Andrew Camp, MD · UCSD Shiley Eye Institute
Study Design
- Allocation
- RANDOMIZED
- Purpose
- OTHER
- Masking
- SINGLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 40 Years
- Max Age
- 90 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2021-12-31
- Primary Completion
- 2022-10-31
- Completion
- 2023-01-31
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