A Study of SGN-CD228A in Advanced Solid Tumors
NCT04042480 · Status: TERMINATED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 88
Last updated 2023-03-23
Summary
This trial will study SGN-CD228A to find out whether it is an effective treatment for different kinds of cancer. It will also look at what side effects (unwanted effects) may occur. The study will have two parts. Part 1 of the study will find out how much SGN-CD228A should be given for treatment and how often. Part 2 of the study will use the dose found in Part 1 and look at how safe and effective the treatment is.
Conditions
- Cutaneous Melanoma
- Pleural Mesothelioma
- HER2 Negative Breast Neoplasms
- Non-small Cell Lung Cancer
- Colorectal Cancer
- Pancreatic Ductal Adenocarcinoma
Interventions
- DRUG
-
SGN-CD228A
SGN-CD228A administered into the vein (IV; intravenously)
Sponsors & Collaborators
-
Seagen Inc.
lead INDUSTRY
Principal Investigators
-
Anu Gupta, MD · Seagen Inc.
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-09-03
- Primary Completion
- 2023-03-09
- Completion
- 2023-03-09
- FDA Drug
- Yes
Countries
- United States
- France
- Italy
- Spain
- United Kingdom
Study Locations
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