Pulsatile and Steady State Hemodynamics in Diastolic Heart Failure
NCT00720525 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 362
Last updated 2011-07-18
Summary
Over the past few years, there has been a growing appreciation that a large number of patients with heart failure have a relatively normal (or preserved) ejection fraction (NFNEF). Epidemiologically, HFNEF is most prevalent among elderly women, most of whom have hypertension, diabetes, or both and often coronary artery disease (CAD). Increased arterial stiffness and/or wave reflections have been described in the same patient groups. Therefore, the investigators speculate that pulsatile hemodynamics, representing arterial stiffness and/or arterial wave reflections, 1) may be altered in HFNEF patients, 2) this may contribute to pathophysiology of HFNEF, and 3) this may be used for the diagnosis of the syndrome.
Conditions
- Diastolic Heart Failure
Sponsors & Collaborators
-
Klinikum Wels-Grieskirchen
lead OTHER
Principal Investigators
-
Thomas Weber, MD · Cardiology Department, Klinikum Wels-Grieskirchen, Austria
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2008-04-30
- Completion
- 2011-07-31
Countries
- Austria
Study Locations
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