High Dose of Vitamin C on Mechanically Ventilated Septic Patients in Intensive Care Unit
NCT04029675 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40
Last updated 2020-07-21
Summary
Prospective, Randomized clinical trial study will be carried out in intensive care unit in Ain Shams University Hospitals on 40 forty septic patients admitted to ICU and mechanically ventilated.
Conditions
- Ventilator Associated Pneumonia ( VAP)
- Sepsis
Interventions
- DIETARY_SUPPLEMENT
-
Vitamin C
Vitamin C is a strong antioxidant and has been shown to regenerate other antioxidants such as vitamin E, vitamin C also play an important role in immune function
Sponsors & Collaborators
-
Ain Shams University
lead OTHER
Principal Investigators
-
Sara M. Shahen, MD · Ain Shams University
-
Ibrahim E. Mamdoh, MD · Ain Shams University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- OTHER
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 85 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-07-15
- Primary Completion
- 2020-01-15
- Completion
- 2020-02-15
Countries
- Egypt
Study Locations
More Related Trials
-
Ascorbic Acid (Vitamin C) Infusion in Human Sepsis
NCT01434121 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Vitamin C and Septic Shock
NCT03338569 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Early Administration of Vitamin C in Patients With Sepsis or Septic Shock in Emergency Departments
NCT04747795 ·Status: COMPLETED ·Phase: PHASE3
-
Outcome Following Vitamin C Administration in Sepsis
NCT01590303 ·Status: UNKNOWN ·Phase: PHASE2
-
Study on the Improvement of Microcirculation in Patients With Sepsis by Vitamin B6, Vitamin B12 and Vitamin C
NCT06749756 ·Status: RECRUITING ·Phase: NA
-
Vitamin C to Reduce Vasopressor Dose in Septic Shock
NCT03835286 ·Status: WITHDRAWN ·Phase: PHASE3
-
The Effect of High Dose Parenteral Ascorbic Acid On Microcirculation In Sepsis
NCT04773717 ·Status: COMPLETED ·Phase: NA
-
Vitamin C Infusion for Treatment in Sepsis Induced Acute Lung Injury
NCT02106975 ·Status: COMPLETED ·Phase: PHASE2
-
Effect of Anti-inflammatory and Anti-microbial Co-supplementations in Traumatic ICU Patients at High Risk of Sepsis
NCT04216459 ·Status: COMPLETED ·Phase: NA
-
Effect of Intravenous Vitamin C on SOFA Score Among Septic Patients
NCT04137276 ·Status: COMPLETED ·Phase: NA
-
Vitamin C & Thiamine to Treat Sepsis and Septic Shock
NCT03592277 ·Status: COMPLETED ·Phase: PHASE2
-
Vitamin C, Vitamin B1 and Steroid in Sepsis
NCT04039815 ·Status: UNKNOWN ·Phase: PHASE4
-
Effects of Glucocorticoid Combined With Vitamin C and Vitamin B1 on Microcirculation in Severe Septic Shock
NCT03821714 ·Status: COMPLETED ·Phase: NA
-
Vitamin C Infusion for TReatment in Sepsis and Alcoholic Hepatitis
NCT03829683 ·Status: COMPLETED ·Phase: PHASE2
-
Clinical Efficacy of Megadose Vitamin C in Sepsis
NCT05194189 ·Status: COMPLETED ·Phase: PHASE2
-
Vitamin C, Thiamine and Hydrocortisone for the Treatment of Septic Shock
NCT03872011 ·Status: COMPLETED ·Phase: PHASE3
-
High-dose Intravenous Vitamin C in Patients With Septic Shock
NCT04796636 ·Status: UNKNOWN ·Phase: PHASE1
-
The Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock Trial
NCT03333278 ·Status: COMPLETED ·Phase: PHASE2
-
Therapy With Hydrocortisone, Ascorbic Acid, Thamine in Patients With Sepsis
NCT04160676 ·Status: COMPLETED ·Phase: NA
-
High-dose Intravenous Vitamin C as an Adjunctive Treatment for Sepsis in Rwanda
NCT04088591 ·Status: WITHDRAWN ·Phase: PHASE3
-
Ascorbic Acid and Thiamine Effect in Septic Shock
NCT03756220 ·Status: COMPLETED ·Phase: PHASE2
-
Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock
NCT05192213 ·Status: TERMINATED ·Phase: PHASE3
-
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Sepsis and Septic Shock
NCT03258684 ·Status: COMPLETED ·Phase: NA
-
Evaluation of Hydrocortisone, Vitamin C and Thiamine for the Treatment of Septic Shock
NCT03380507 ·Status: TERMINATED ·Phase: PHASE2/PHASE3
-
Triple Therapy in Septic Shock Patients
NCT04508946 ·Status: COMPLETED ·Phase: PHASE3