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Hyperpolarized 129Xe MRI for the Assessment of BOS With Late Onset LONIPC

NCT04029636 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 45

Last updated 2019-07-23

No results posted yet for this study

Summary

The development of bronchiolitis obliterans syndrome (BOS) and other late onset non-infectious pulmonary complications (LONIPCs) following hematopoietic stem cell transplantation (HSCT) is associated with a significantly worse prognosis, high disease burden, and excessive health resource utilization. In this proposal, the investigators plan to examine and compare different diagnostic modalities which can provide detailed physiological and anatomical characterization of LONIPCs.

Conditions

  • Bronchiolitis Obliterans

Interventions

OTHER

Inhaled Hyperpolarized Xenon-129

How hyperpolarized 129Xe MRI measurements of lung structure and function change over time in a population at high risk for LONIPC related to their transplant

Sponsors & Collaborators

  • Hamilton Health Sciences Corporation

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-08-31
Primary Completion
2021-08-31
Completion
2021-11-30

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04029636 on ClinicalTrials.gov