Cardiovascular Effects of CART Cell Therapy
NCT04026737 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 44
Last updated 2026-02-09
Summary
This is an observational study aiming to prospectively define the rate of occurrence, natural history and progression of cardiac dysfunction in adults, and to identify the patients at high risk of developing cardiovascular events. The study enrolls patients prior to infusion with CART cell therapy and follows them with serial echocardiography, cardiac biomarkers, clinical data, and quality of life questionnaire.
Conditions
- Leukemia
- Lymphoma
- Cardiotoxicity
- Risk Factor, Cardiovascular
- Immunotherapy
Sponsors & Collaborators
-
Abramson Cancer Center at Penn Medicine
lead OTHER
Principal Investigators
-
Marielle Scherrer-Crosbie, MD, PhD · University of Pennsylvania
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-07-22
- Primary Completion
- 2022-11-16
- Completion
- 2022-11-16
Countries
- United States
Study Locations
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