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Monofocal Extended Range of Vision (MERoV) Study

NCT04011696 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 412

Last updated 2023-11-03

No results posted yet for this study

Summary

The investigators are proposing this research project to:

1. Screen a set of patients after normal cataract surgery with a single focus lens aimed at good distance vision at 3 months after surgery to identify patients who are able to see and read well without glasses.
2. Identify the combination of factors responsible for this phenomenon in the patients who are achieving this.

Potentially eligible patients will be given an invitation letter and patient information sheet on the day they arrive for surgery. They will then be asked if they are happy to be contacted by phone 2-4 weeks post-surgery with a view to booking them into an additional research visit at 3 months after their surgery. At 3 months after surgery they will have their un-corrected vision checked. They will also have their reading speed assessed without any glasses. They will undergo a through refractive check by an optometrist to assess the power of the spectacles (if needed) and following this they will have a scan of the eye (a technique known as wave front analysis which uses very sophisticated optics) to capture the optical distortions in the structures of the eye.

If this study is able identify factor/s responsible for giving good unaided reading and distance vision then this factor can be reproduced in eyes undergoing cataract surgery. This will mean that the patients can have an increased option of spectacle independence without the need for expensive multifocal IOLs and their associated side effects such as glare and halos, particularly at night.

Conditions

  • Pseudophakia
  • Accomodation
  • Aberration, Corneal Wavefront

Sponsors & Collaborators

  • King's College London

    collaborator OTHER

  • European Society of Cataract and Refractive Surgeons

    collaborator OTHER

  • Brighton and Sussex University Hospitals NHS Trust

    lead OTHER

Principal Investigators

  • Mayank A Nanavaty, FRCOphth,PhD · Brighton and Sussex University Hospitals NHS Trust

  • David J Spalton, FRCOphth · King's College London

  • Catey Bunce, DSc · King's College London

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-07-03
Primary Completion
2022-05-31
Completion
2022-05-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04011696 on ClinicalTrials.gov