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The DETECT HCV Screening Trial

NCT04003454 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 147533

Last updated 2025-02-06

No results posted yet for this study

Summary

The investigators propose to compare the effectiveness of nontargeted rapid opt-out hepatitis C (HCV) screening versus targeted rapid opt-out HCV screening using recommended risk characteristics in multiple urban emergency departments (EDs) across the United States (Aim 1 - "Screening Trial").

Conditions

  • Hepatitis C

Interventions

OTHER

HCV Screening

The investigators will perform a prospective pragmatic randomized effectiveness trial that will allow the investigators to directly compare 2 HCV screening methods while minimizing threats to internal validity. Patients will be screened for HCV infection using 1 of 2 interventions using a balanced patient-level random allocation scheme built into existing EHRs for each ED.

Sponsors & Collaborators

  • Johns Hopkins University

    collaborator OTHER

  • University of Mississippi Medical Center

    collaborator OTHER

  • Boston University

    collaborator OTHER

  • Boston Medical Center

    collaborator OTHER

  • University of Cincinnati

    collaborator OTHER

  • Alameda County Medical Center

    collaborator OTHER

  • Denver Health and Hospital Authority

    lead OTHER

Principal Investigators

  • Jason Haukoos, MD, MSc · Denver Health

  • Sarah Rowan, MD · Denver Health

Study Design

Allocation
RANDOMIZED
Purpose
SCREENING
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-11-20
Primary Completion
2023-07-31
Completion
2024-01-31

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04003454 on ClinicalTrials.gov