Early Detection of HCV in Injection Drug Users

Summary

The project is a national, prospective, multicenter, non-interventional pilot project of screening HCV in PWID in the Czech Republic.

The main goal of the project is to methodically prepare, implement and evaluate a pilot project that will verify the suitability of the proposed procedure of early detection of Hepatitis C and setting up and testing new methods and implementation into the system of social health care.

Conditions

• Hepatitis C Virus Infection

Interventions

DIAGNOSTIC_TEST

Hepatitis C antibody (anti-HCV) test

Testing for hepatitis C antibodies determines whether or not you have been exposed to HCV at some point in your life. This testing will be performed in all 3,000 persons who inject drugs enrolled in the project.

DIAGNOSTIC_TEST

Hepatitis C RNA test and genotype test

RNA is a type of genetic material from HCV that can be detected in the blood. This test will be used as a confirmation of the infection. This testing will be performed in all persons with positive antibody test who will come to clinical center.

Sponsors & Collaborators

• Institute for Clinical and Experimental Medicine

  collaborator OTHER_GOV

• Brno University Hospital

  collaborator OTHER

• České Budějovice Hospital

  collaborator OTHER

• University Hospital Hradec Kralove

  collaborator OTHER

• University Hospital Olomouc

  collaborator OTHER

• Hepatogastroenterology Hradec Kralove

  collaborator UNKNOWN

• Regional Hospital Karlovy Vary

  collaborator UNKNOWN

• Clinic Podane ruce

  collaborator UNKNOWN

• Tomáš Baťa Regional Hospital in Zlín

  collaborator UNKNOWN

• Hospital Agel Prostějov

  collaborator UNKNOWN

• Hospital Jihlava

  collaborator UNKNOWN

• Hospital Havířov

  collaborator UNKNOWN

• Hospital Tábor

  collaborator UNKNOWN

• Remedis Prague

  collaborator UNKNOWN

• Hospital Opava

  collaborator UNKNOWN

• Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.

  collaborator OTHER

• Military University Hospital, Prague

  collaborator OTHER

• Hospital Pardubice

  collaborator UNKNOWN

• Institute of Health Information and Statistics of the Czech Republic

  lead OTHER_GOV

Principal Investigators

• Viktor Mravcik, assoc. prof. · Charles University First Faculty of Medicine

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2023-12-15

Primary Completion

2025-12-31

Completion

2025-12-31

Countries

• Czechia

Study Locations