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Periarticular Injection Versus Peripheral Nerve Block in Total Hip Arthroplasty

NCT03977454 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 192

Last updated 2022-09-23

Study results available
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Summary

This study will assess if preoperative quadratus lumborum block (QLB)/lateral femoral cutaneous nerve block (LFCNB) with ropivacaine and glucocorticoids provide more effective analgesia than periarticular injection (PAI) with the same mixture in total hip arthroplasty (THA).

Conditions

  • Hip Arthropathy

Interventions

PROCEDURE

Nerve Block

Nerve blocks (QLB/LFCNB) to be placed preoperatively with DEX/MPA, per standard of care of anesthesia block service. 1. QLB: 40ml 0.2% ropivacaine with 5 mg DEX/ 40 mg MPA 2. LFCNB: 20ml 0.2% ropivacaine with 5 mg DEX/ 40 mg MPA

PROCEDURE

Periarticular Injection (PAI)

Intraoperatively, the surgeon will perform PAI per standard of care with the medications: 1\. 60 ml 0.2% ropivacaine and 10 mg DEX/ 80 mg MPA

DRUG

Ropivacaine

60 ml 0.2% ropivacaine

DRUG

Dex

10 mg DEX/ 80 mg MPA

Sponsors & Collaborators

  • Yale University

    lead OTHER

Principal Investigators

  • Jinlei Li, MD PhD FASA · Yale University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-11-11
Primary Completion
2021-06-19
Completion
2021-06-19
FDA Drug
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03977454 on ClinicalTrials.gov