Geriatric Core Dataset (G-CODE) for Clinical Research in Elderly Cancer Patients

Summary

Older adults with cancer remain underrepresented in cancer clinical trials that establish new standards of care. Geriatric assessment (GA) is defined by geriatricians as a multidimensional interdisciplinary assessment of the general health stat us of the older patient, reviewing the medical, psychosocial, functional and environmental domains. For each domain, several tools are available, but consensus is lacking on which tool to use and the optimal cut-offs or threshold scores. The literature supports the prognostic value of the GA and its utility in weighing the benefits and risks of cancer treatments in older adults. However, GA has not been implemented in routine oncology practice or in cancer clinical trials.

The objective of this project is to develop a set of geriatric data, the Geriatric Core Dataset (G-CODE), to be collected in cancer trials of older patients. The methods rely on a consensus process involving international experts in the field of oncology and geriatrics.

Conditions

• Cancer

Sponsors & Collaborators

• Plate-forme PACAN (Elderly and Cancer Platform)

  collaborator OTHER

• European Georges Pompidou Hospital

  collaborator OTHER

• Hospital Ambroise Paré Paris

  collaborator OTHER

• Institut Curie

  collaborator OTHER

• Centre Leon Berard

  collaborator OTHER

• Institut Claudius Regaud

  collaborator OTHER

• Saint-Louis Hospital, Paris, France

  collaborator OTHER

• Hospital Avicenne

  collaborator OTHER

• Göteborg University

  collaborator OTHER

• Oslo University Hospital

  collaborator OTHER

• City of Hope Comprehensive Cancer Center

  collaborator OTHER

• Institut Bergonié

  lead OTHER

Principal Investigators

• Simone Mathoulin-Pélissier, MD/PhD · Institut Bergonié

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2015-01-01

Primary Completion

2017-01-01

Completion

2017-01-01

Countries

• France

Study Locations