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Prevalence of Wild Type ATTR

NCT03966105 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 94

Last updated 2023-03-27

No results posted yet for this study

Summary

Prospective, observational, single-centre, non-interventional study aiming at reporting the prevalence of ATTRwt in patients with lumbar spinal stenosis (LSS).

Conditions

  • Wild-type Transthyretin Amyloidosis

Interventions

DIAGNOSTIC_TEST

HE and Congo red staining

Biopsies will be formalin fixed, processed routinely, and sent to the Department of Pathology for evaluation by hematoxylin and eosin and Congo red staining by pathologists. Biopsy specimens with confirmed amyloid deposits via Congo red staining will be further analyzed using immunohistochemistry for subtyping.

Sponsors & Collaborators

  • University of Kiel

    collaborator OTHER

  • Ente Ospedaliero Cantonale, Bellinzona

    collaborator OTHER

  • Oncology Institute of Southern Switzerland

    lead OTHER

Principal Investigators

  • Adalgisa Condoluci, MD · Oncology Institute of Southern Switzerland

Eligibility

Min Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-11-01
Primary Completion
2021-10-31
Completion
2022-10-31

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03966105 on ClinicalTrials.gov