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Identification of Stroke Patients ≤ 3 and ≤ 4.5 Hours of Symptom Onset by Fluid Attenuated Inversion Recovery (FLAIR) Imaging and Diffusion Weighted Imaging (DWI)

NCT01021319 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 643

Last updated 2019-04-16

No results posted yet for this study

Summary

The aim of the study is to evaluate the use of combined fluid attenuated inversion recovery (FLAIR) imaging and diffusion weighted imaging (DWI) as surrogate marker of lesion age within the first 6 hours of ischemic stroke in order to identify patients ≤ 3 or ≤ 4.5 hours of symptom onset in a large multicenter study hours of ischemic stroke. The investigators hypothesize that the pattern of a visible lesion on DWI together with a negative FLAIR ("DWI-FLAIR mismatch") will identify patients ≤ 3 hours of symptom onset with \>80% specificity and positive predictive value.

Conditions

  • Acute Ischemic Stroke

Sponsors & Collaborators

  • Else Kröner-Fresenius-Stiftung (Foundation)

    collaborator UNKNOWN

  • Stroke Imaging Repositoy (STIR)

    collaborator UNKNOWN

  • MR Stroke Group

    collaborator UNKNOWN

  • Götz Thomalla, MD

    lead OTHER

Principal Investigators

  • Götz Thomalla, MD · Uinversity Medical Center Hamburg-Eppendorf

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-09-30
Primary Completion
2010-05-31
Completion
2010-05-31

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01021319 on ClinicalTrials.gov