Exploratory Clinical Study of Apatinib and PD-1 in Treating Advanced Gastric Cancer
NCT03954756 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 35
Last updated 2019-05-17
Summary
The Purpose of This Study is to Evaluate the Efficacy and Safety of Apafitini Combined With PD1 in Patients With Advanced Gastric Cancer After Second-line Treatment Failure, Thus Providing More Options for Patients With Advanced Gastric Cancer.
Conditions
- Advanced Gastric Cancer
Interventions
- DRUG
-
Apatinib and PD1
1. Apatinib starting dose of 500mg, qd, oral, taken half an hour after a meal 2. PD-1 was administered 200mg (3mg/kg for underweight patients) iv every 2 weeks.
Sponsors & Collaborators
-
Henan Cancer Hospital
lead OTHER_GOV
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-06-01
- Primary Completion
- 2021-06-01
- Completion
- 2021-06-01
More Related Trials
-
Efficacy and Safety of Apatinib Combined With S-1 for Patients With Advance Gastric Cancer
NCT04338438 ·Status: COMPLETED ·Phase: PHASE2
-
Apatinib in Combination With S-1 as First-Line Treatment in Patients With Advanced Gastric Cancer
NCT02525237 ·Status: UNKNOWN ·Phase: PHASE2
-
The Maintenance Treatment of Apatinib/Capecitabine Versus Observation in Advanced Gastric Cancer
NCT03889626 ·Status: UNKNOWN ·Phase: PHASE3
-
A Study of Apatinib Combined With S1 in Patients With Advanced Gastric Cancer
NCT03271073 ·Status: UNKNOWN ·Phase: PHASE2
-
Clinical Trial of Apatinib Reverses Chemotherapy-Resistance of Patients With Advanced Gastric Cancer
NCT02697838 ·Status: UNKNOWN ·Phase: PHASE2
-
Apatinib Combined With Chemotherapy Versus Chemotherapy in Second-line Gastric Cancer Receiving Prior Anti-PD-1 Therapy
NCT05029453 ·Status: UNKNOWN ·Phase: PHASE4
-
Apatinib Combined With Capecitabine Second-line Treatment of Advanced Gastric Cancer: a Single-arm Exploratory Clinical Pilot Trial
NCT03531931 ·Status: UNKNOWN
-
PD-1 Antibody + Apatinib Mesylate in 2+ Line Serum AFP-elevated Gastric Adenocarcinoma
NCT04006821 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study of SHR-1210 in Combination With Capecitabine + Oxaliplatin or Apatinib in Treatment of Advanced Gastric Cancer
NCT03472365 ·Status: COMPLETED ·Phase: PHASE2
-
A Clinical Trial of Maintenance Treatment of Apatinib in Advanced Gastric Cancer Patients Have Completed Postoprative Adjuvant Chemotherapy
NCT02776527 ·Status: UNKNOWN ·Phase: PHASE4
-
Apatinib Combined With Paclitaxol as Second Line Therapy for Advanced Gastric Cancer.
NCT03144843 ·Status: UNKNOWN ·Phase: PHASE2
-
Apatinib as Maintenance Therapy After First Line Treatment in Locally Advanced or Metastatic Gastric Cancer
NCT02537171 ·Status: UNKNOWN ·Phase: PHASE3
-
Apatinib as Maintenance Therapy After Adjuvant Chemotherapy in Progressive Gastric Cancer With Positive Exfoliative Cancer Cells
NCT02510469 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Apatinib Combined With POF for Second-line Treatment of Gastric Adenocarcinoma
NCT03788174 ·Status: UNKNOWN ·Phase: PHASE2
-
The Real World Study of Apatinib for Gastric Cancer Treatment in Anhui Province
NCT03333967 ·Status: UNKNOWN
-
Apatinib Plus Docetaxel Versus Docetaxel as Second-line Treatment in Advanced Gastric Cancer (AHEAD-301)
NCT02596256 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study of Apatinib Tablets in the Treatment of Advanced or Metastatic Gastric Cancer
NCT02426034 ·Status: COMPLETED ·Phase: PHASE4
-
The Real World Study of Apatinib for Gastric Cancer Treatment in Henan Province
NCT03478943 ·Status: UNKNOWN
-
Apatinib Combined With S-1 as Maintenance Therapy for HER-2 Negatived Gastric Cancer
NCT03950141 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study of Intraperitoneal and Intravenous Paclitaxel Plus Apatinib and S-1 Conversion Therapy for Gastric Cancer With Positive Exfoliative Cancer Cells
NCT03718624 ·Status: UNKNOWN ·Phase: PHASE2
-
Apatinib Combined With SOX Neoadjuvant Therapy for Locally Advanced Gastric Cancer
NCT03192735 ·Status: UNKNOWN ·Phase: PHASE2
-
Research On the Optimized Treatment Method For Apatinib's Cure Of Advanced Gastric Cancer
NCT03334591 ·Status: UNKNOWN ·Phase: PHASE2
-
Evaluate the Efficacy of Maintenance Treatment With Capecitabine Plus Apatinib in Advanced Gastric Cancer
NCT03598348 ·Status: UNKNOWN ·Phase: PHASE3
-
The Study of Apatinib Plus CIK as the Third Line Therapy for Patients With Advanced Gastric Cancer
NCT02485015 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Apatinib with Oxaliplatin and S-1 Treatment for Advanced Hepatoid Adenocarcinoma of the Stomach
NCT04863430 ·Status: WITHDRAWN ·Phase: PHASE2