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Treating Postictal Symptoms Using Ibuprofen and Nifedipine

NCT03949478 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 90

Last updated 2024-05-09

No results posted yet for this study

Summary

This study will evaluate the effect of ibuprofen or nifedipine on post-seizure hypoperfusion and neurological deficits in patients with epilepsy. One group will receive ibuprofen, another will receive nifedipine, and anther placebo.

Conditions

Interventions

DRUG

Ibuprofen

Ibuprofen to be prepared in a tablet that is not distinguishable from nifedipine or placebo tablet.

DRUG

Nifedipine

Nifedipine to be prepared in a tablet that is not distinguishable from ibuprofen or placebo tablet.

DRUG

Placebo

Sugar pill to be prepared in a tablet that is not distinguishable from ibuprofen or nifedipine tablet.

Sponsors & Collaborators

  • University of Calgary

    lead OTHER

Principal Investigators

  • Paolo Federico, MD, PhD · University of Calgary

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
16 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-02-01
Primary Completion
2025-01-01
Completion
2025-03-01

Countries

  • Canada

Study Locations

More Related Trials

Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03949478 on ClinicalTrials.gov